athenahealth doesn't see patients. It runs the billing, charts, and reminders for the clinicians who do - and it's betting the whole network on AI.
The company betting that the most expensive corner of American medicine - cancer, cardiology, and back surgery - can be run better when the people paying for care and the doctors delivering it are finally pulling in the same direction.
Castor is a health-technology company that builds a cloud-based eClinical platform for running clinical trials - from electronic data capture (EDC) and eConsent to eCOA/ePRO and real-world evidence. Founded in 2012 in Amsterdam by physician-researcher Dr. Derk Arts, Castor set out to replace clunky, expensive trial software with a self-service, researcher-friendly system. Today it supports more than 15,000 studies across 90+ countries and is used by leading CROs and biopharma companies, while pushing decentralized trials and practical AI (Castor Catalyst, built with Google Cloud) into mainstream research.
Ethermed is a Philadelphia-based health technology company that uses large language models and clinical reasoning to automate prior authorization - the paperwork-heavy approval process between healthcare providers and insurers. Its platform intercepts physician orders, gathers documentation, compares payer guidelines, fills forms and submits requests with an audit trail, cutting approval times from days to minutes. Founded in 2021 by Dan Friedman and Michal Such, the company raised an $8.5M Series A in April 2026, bringing total funding above $15M.
Redox is a Madison, Wisconsin-based healthcare technology company that runs a cloud network for exchanging clinical and administrative data between health systems, digital health vendors, payers, and life sciences companies. Founded in 2014 by three former Epic Systems engineers, Redox lets a customer connect once to a single API and then reach thousands of healthcare organizations across dozens of electronic health record systems, rather than building and maintaining hundreds of point-to-point integrations. The platform handles standards like HL7v2, CCD, X12, and FHIR, and processes billions of data transactions a year.
Vital Interaction is an Austin, Texas healthcare technology company that blends patient data, business intelligence, and workflow automation to help medical practices communicate with patients across text, voice, and email. Founded in 2009, its platform automates appointment reminders, recalls, reactivations, referrals, and surveys so practices can cut no-shows, close care gaps, and re-engage patients. The company says it serves more than 13,000 providers and delivers over 40 million personalized messages a year to more than 5 million patients, and in early 2024 it raised a $15 million Series A led by Next Coast Ventures.
DeepScribe is a San Francisco-based health-tech company building an ambient AI medical scribe that listens to natural doctor-patient conversations and turns them into complete, structured clinical notes in real time. Founded in 2017, the company has narrowed its focus to oncology, where it says it serves roughly 90% of U.S. community oncology organizations, and layers on tools for coding, pre-visit prep, and specialty-specific customization. The pitch is straightforward: let clinicians look at their patients instead of their keyboards, and cut the after-hours documentation that drives burnout.
Theator is a surgical intelligence company that turns raw operating-room video into structured, actionable data. Using proprietary computer vision and AI, its platform analyzes minimally invasive procedures in real time - identifying surgical steps, flagging safety milestones, and generating operative reports by the time the surgeon leaves the OR. Founded by Dr. Tamir Wolf and Dotan Asselmann, Theator aims to reduce variability in surgical care and is deployed at academic medical centers including Mayo Clinic and UHealth Miami, having analyzed more than 600,000 procedures.
Acentra Health is a McLean, Virginia healthcare technology and clinical services company formed in 2023 from the merger of CNSI and Kepro. It builds Medicaid and Medicare systems, care management platforms, and quality-oversight services for state and federal government health programs, combining public-sector software with clinical staff who review authorizations, assessments, and appeals. Backed by The Carlyle Group, it employs roughly 3,300-3,400 people across the U.S. and India.
PARx Solutions is a Burlington, Massachusetts healthcare technology and services company that untangles one of medicine's most frustrating chores: prior authorization. Its Prior Authorization Support System (PASS) pairs a secure web portal with a call center of healthcare and reimbursement specialists who handle the paperwork and back-and-forth with health plans on a prescriber's behalf. Because the service is sponsored by drug manufacturers, it is free to physician offices and pharmacies, and it helps patients actually get the medications their doctors prescribed rather than abandoning treatment in the administrative maze.
Pascal Metrics is a Washington, DC and Austin-based healthcare data analytics company that turns real-time electronic health record data into clinically validated adverse-event outcomes. As a U.S.-certified Patient Safety Organization (PSO #0047), it operates the Pascal Platform - anchored by trigger-based surveillance and machine-learning models - to help hospitals and health systems detect, predict, and reduce preventable patient harm. Founded in 2007 and named after Blaise Pascal, the 'founder of risk management,' the company claims one of the largest validated adverse-event outcomes datasets in the world.
Trayt Health is a Menlo Park, California company building a patient-centric, clinician-directed software platform that coordinates behavioral and mental health care across primary care, schools, and specialty clinicians. Its platform powers statewide psychiatry access programs and managed care organizations by tracking 750+ symptoms and factors, streamlining consultations and referrals, and turning granular patient data into population-level insights. As of 2026 it supports roughly 20 statewide behavioral health programs across eight U.S. states.
NexHealth is a San Francisco-based health technology company building the patient experience platform for medical and dental practices. Its software gives doctors EHR-integrated online scheduling, patient messaging, digital paperwork, recalls, reviews and payments, while its Universal API and proprietary Synchronizer let developers read and write data across 20+ practice management systems in real time. Founded in 2017 by Alamin Uddin and Waleed Asif, NexHealth reached unicorn status in 2022 with a $125M Series C at a $1B valuation and serves more than 10,000 practices.
Health Note is a healthcare AI company that automates the administrative work surrounding a clinical visit. Founded by physician Joshua Reischer, MD, its platform collects patient information before an appointment through conversational texting and AI voice agents, then turns that data into structured EHR documentation and pre-written clinical notes. The goal is to cut the paperwork and phone-tag that drives physician burnout, shorten check-in times, and let care teams spend more time with patients and less with screens.
Qualified Health is a Palo Alto-based public benefit company building the enterprise AI operating layer for hospitals and health systems. Its platform unifies clinical, operational, and financial workflows under a single governed layer - integrating with core health-system data once, offering pre-validated AI solutions plus builder tools, and adding real-time governance, monitoring, and outcomes tracking. Founded in 2024 by physician-technologist Justin Norden and a team of former health-system executives and AI leaders, it helps systems move past pilots toward scaled, safe, measurable AI. The company has raised $155M to date, including a $125M Series B in March 2026, and serves more than 500,000 users across systems representing roughly 7% of U.S. hospital revenue.
DocSpera is a Sunnyvale-based healthtech company that builds an AI-driven surgical coordination platform connecting surgeons, care teams, hospitals, ambulatory surgery centers and medical-device partners across the full episode of care. Its HIPAA-compliant web and mobile software automates pre-surgical scheduling, patient readiness and prioritization, secure case and image sharing, and surgical inventory and supply-chain management - reducing cancellations, backlogs and wasted inventory while generating real-world evidence on surgical outcomes.
PaxeraHealth is a Boston-area medical imaging company that builds AI-driven enterprise imaging software - PACS, vendor-neutral archives, image sharing, and a no-code platform that lets hospitals author their own imaging algorithms. Founded in 2009 by Dr. Mohamed Shoura, the company has installed thousands of PACS systems across 50+ countries and counts the American College of Radiology and AdventHealth among its clients.
Clarify Health Solutions is a San Francisco-based healthcare analytics company that maps hundreds of millions of patient journeys through its cloud-based Atlas Platform, helping payers, providers, and life sciences companies make smarter decisions about cost, care, and outcomes in the shift to value-based care.