Joe Loy is the President and CEO of Zetagen Therapeutics, a Syracuse, New York clinical-stage biopharmaceutical company developing small-molecule therapies to treat metastatic cancer in bone and soft tissue while regenerating healthy bone. A serial entrepreneur with several successful exits, Loy has spent his career building teams around first-to-market medical technologies at companies including US Surgical, Pfizer/Leibinger, NuVasive, and Stryker. Since taking the helm in January 2019, he has guided Zetagen through two FDA Breakthrough Device Designations, multiple financing rounds, and the launch of Phase 2a clinical trials for its lead candidate ZetaMet.
Luis Alvarez is the founder and CEO of Theradaptive, a Frederick, Maryland biotech engineering proteins that latch onto implants and surgical materials to trigger the body to regrow bone, cartilage, and other tissue exactly where it is needed. A retired U.S. Army lieutenant colonel and MIT-trained biological engineer, he traced the idea back to a combat tour in Iraq, where soldiers under his command lost limbs to delayed amputations. Theradaptive has since won multiple FDA Breakthrough Device Designations, raised more than $43 million, and moved its lead protein, AMP2, into human clinical trials.