Terragia Biofuel is a New Hampshire climate-tech startup turning non-food plant waste into cost-competitive, low-carbon ethanol using engineered thermophilic bacteria. Its consolidated bioprocessing (CBP) approach skips the expensive enzymes and thermochemical pretreatment that have historically sunk cellulosic biofuel economics, promising an 8x shorter payback period at 10x smaller scale. Spun out of Professor Lee Lynd's decades of research at Dartmouth, Terragia aims to make biofuels for hard-to-electrify transport - aviation, shipping, and long-haul trucking - that can actually compete with fossil fuels.
Matterworks is a Somerville, Massachusetts biotech-AI company building foundation models for molecular biology. Its Large Spectral Models (LSMs) are trained on billions of mass spectrometry spectra and read raw molecular signals directly, turning slow, manual mass-spec workflows into automated, untargeted absolute quantitation. Its flagship cloud platform, Pyxis, acts as a predictive omics assistant that converts raw LC-MS data into identified, quantified molecules and biological insight - making mass spectrometry usable by any biologist rather than only specialist analysts.
Solarbiotech is a U.S.-based synthetic biology and biomanufacturing company that helps companies move precision-fermentation products from lab bench to commercial scale. Built around a Norton, Virginia plant with fermentation capacity from 6L to 10,000L and a modular 'BioNodes' architecture, it offers end-to-end strain-to-shelf services - upstream fermentation, downstream processing, and commercial production - for food ingredients, nutraceuticals, cosmetics, enzymes, and industrial bioproducts. After a 2024 Chapter 11 restructuring, its assets were acquired by Pictor Biotech (led by ex-Novozymes executive Peter Rosholm) and unified in January 2025 with GPC Bio and Eleszto Genetika into a vertically integrated, 100+ person SynBio platform.

Eric Abbate is a synthetic-biology scientist turned CEO who led Solar Biotech, a Virginia-based startup building solar-powered, water-neutral fermentation plants to make biodesigned cosmetics, food ingredients and bioelectronic components. A UC Berkeley-trained molecular and cell biologist, he ran high-throughput genome-engineering and analytical biochemistry teams at Inscripta and was corresponding author on a widely cited paper on optimizing strain engineering for industrial-scale production. He steered Solar Biotech from lab science toward a modular 'BioNodes' manufacturing model before the company entered Chapter 11 in 2024 with plans to sell its assets and reboot.
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) for cell therapy. Its Cell Shuttle - a fully automated, high-throughput platform roughly the size of a small conference room - replaces a warren of manual labs with one box that can run 16 patient batches in parallel, cutting labor and facility footprint by about 90 percent.
Fabian Gerlinghaus is the Co-Founder and CEO of Cellares, a South San Francisco biotech company building the world's first Integrated Development and Manufacturing Organization (IDMO) for cell therapy. An aerospace engineer turned life-science entrepreneur, he co-founded Cellares in 2019 after spotting a critical gap: FDA-approved CAR-T therapies were sitting ready while patients died on waitlists because manufacturing couldn't scale. His Cell Shuttle platform — a fully automated, factory-in-a-box system processing 16 patient batches simultaneously — has attracted $630M in funding, a $380M partnership with Bristol Myers Squibb, and FDA's Advanced Manufacturing Technology designation. TIME magazine named it one of 2025's most important inventions.
Stämm is a deep-tech biomanufacturing company building a desktop-scale, 3D-printed, bubble-free bioprocessor that replaces the giant stainless-steel tanks of conventional pharma. Founded in Buenos Aires and headquartered in San Francisco, the company is pursuing a vision of decentralized, AI-driven production of biologics and cell therapies.
Yuyo Llamazares Vegh is the CEO and Co-Founder of Stämm, a San Francisco-based biotech company reinventing biomanufacturing through miniaturized 3D-printed microfluidic bioreactors. A native of Argentina with a background in agricultural engineering and bioprocesses from the University of Buenos Aires, Yuyo co-founded Stämm in 2016 alongside his cousin Federico D'Alvia Vegh after spotting a fundamental gap between biology's potential and the outdated tools available to harness it. Stämm's platform - desktop-sized, modular, and scalable - is designed to make the production of biologics, cell therapies, and gene therapies accessible and repeatable at any scale. The company has raised over $17 million including a Series A led by Varana Capital with participation from Draper Associates and SOSV's IndieBio, and has attracted former Merck KGaA CEO Stefan Oschmann to its board. Yuyo was selected as an Endeavor Entrepreneur in 2023.