Ana-Maria Constantin is the CEO and co-founder of Cascade AI, a Bellevue-based startup building agentic AI that automates the grind of HR and back-office operations. A Harvard dual major in computer science and astrophysics who left Romania after high school, she spent five-plus years as a software engineer at Microsoft writing code that touched millions of users on Azure before deciding HR - the function that touches more lives than any other in a company - was the perfect place to point machine learning. She raised a $5.45M-plus seed round led by Google's Gradient Ventures with AlleyCorp, was named GeekWire's Young Entrepreneur of the Year in 2024, and recognized as a 2025 Google Cloud Partner All-Star.
Dr. Katherine (Katie) Mack is a theoretical astrophysicist, science communicator, and author who holds the inaugural Hawking Chair in Cosmology and Science Communication at the Perimeter Institute for Theoretical Physics. Known online as @AstroKatie with over 400,000 Twitter/X followers, she studies the fundamental questions of how the universe will end - dark matter, vacuum decay, primordial black holes - and makes it all thrillingly accessible. Her 2020 book 'The End of Everything (Astrophysically Speaking)' was a New York Times Notable Book. She publishes 'The Last Star' newsletter, co-hosted a podcast with John Green, is an instrument-rated pilot, and was name-dropped by Hozier in a Grammy-winning album.