Journey Clinical is a New York-based healthtech company that operates a collaborative-care platform enabling licensed psychotherapists to offer Ketamine-Assisted Psychotherapy (KAP) inside their own private practices. Its in-house medical team handles patient eligibility, ketamine prescriptions, and ongoing medical monitoring, while therapists deliver the preparation, dosing, and integration sessions. The model expands safe, legal access to psychedelic-assisted care for patients with depression, anxiety, PTSD, and other conditions, and has grown to a network of over 2,500 trained providers.
Arcade Therapeutics is a New York-based digital therapeutics company that builds clinically validated mobile games to treat mental illness. Founded by healthcare entrepreneur Raj Amin and neuroscientist Tracy Dennis-Tiwary, the company embeds a research-backed technique called attention bias modification into engaging games, starting with StarStarter for anxiety. Its lead prescription product, ABM-01, is pursuing FDA submission as one of the first game-based treatments for social anxiety disorder, with a pipeline extending to depression, addiction, and other conditions.
Wonder Sciences is a Los Angeles-based mental health and research company reengineering psychiatric care through psychedelic medicine, clinical research, and AI. Best known for its consumer brand Wondermed - an at-home, low-dose ketamine-assisted telehealth protocol for anxiety and depression - the company is building an AI-native clinical operating system that fuses medication, therapy, and behavioral data into actionable insights. Founded by Ryan Magnussen in 2022, it raised roughly $4.6M-$5.6M in seed funding from investors including Aubrey Marcus and James Foster.
Raj Amin is the co-founder and CEO of Arcade Therapeutics, a New York science-first game studio building prescription digital therapeutics that embed clinically proven anxiety-reduction techniques inside mobile games. A University of Pennsylvania-trained engineer and Wharton MBA, he has spent more than two decades building venture-backed companies at the seam of healthcare, media and technology - including HealthiNation, the first on-demand consumer health video network, and Mana Health, a health-data interoperability platform later acquired by Comcast. He is a self-described #GirlDad, a drummer and aspiring guitarist, and a Broadway investor who has backed Tony Award-winning productions.
Foresight Mental Health is a Berkeley, California-based outpatient mental health provider that pairs clinicians - psychiatrists, therapists and prescribers - with software, data and wearables to deliver personalized, insurance-covered care. Founded by two UC Berkeley computer-science students, the company offers therapy, psychiatry, child and adolescent services, ADHD testing, intensive outpatient programs and TMS across in-person clinics and telehealth, with the stated mission of improving access to high-quality mental health care.
Newleos Therapeutics is a Boston-based, clinical-stage biotechnology company building a new generation of treatments for neuropsychiatric disorders. Launched in February 2025 with an oversubscribed $93.5 million Series A, the company in-licensed four clinical-ready oral small molecules from Roche - targeting GABAA-y1, V1a, TAAR1, and GABAA-a5 - aimed at generalized anxiety, social anxiety, substance use disorders, and cognitive impairment. Its name nods to 'eos,' the Greek word for dawn: a new dawn for mental health treatment.
Sensorium Therapeutics is a Boston-based biotechnology company building first-in-class central nervous system (CNS) medicines by decoding nature's neuroactive chemistry with AI. Founded out of Massachusetts General Hospital and Harvard, its proprietary SensAI platform mines more than 50 million curated relationships across ethnopharmacology, chemistry, pharmacology, and clinical outcomes to identify de-risked starting points for new drugs. Its lead program, SNTX-2643, is a rapid-acting precision serotonin modulator for anxiety that received FDA IND clearance in 2025.
InStride Health is a Boston-based virtual specialty clinic that treats anxiety and OCD in kids, teens, and young adults ages 7 to 24. Founded by Harvard-trained clinicians from McLean Hospital, it delivers insurance-covered, evidence-based care - cognitive behavioral therapy with exposure and response prevention - through a dedicated three-person care team that coaches patients in the real-world settings where their anxiety actually shows up: school, home, the dinner table. The company has raised $56 million and operates across the Northeast.