2048 Ventures closes oversubscribed $82,048,000 Fund III Sandra Pérez Baos promoted to Senior Associate 32 published papers in immunology and molecular biology Scientist. Founder. Investor. In that order Backing biotech from pre-seed to platform acquisition Nucleate New York founding team member PhD in Molecular Biosciences, Universidad Autónoma de Madrid Harvard Business School CORe - Pass with High Honors Investment range $500K - $3M, sweet spot $1.3M Predicting a wave of mid-cap pharma acquisitions in RNA and immunology in 2026 2048 Ventures closes oversubscribed $82,048,000 Fund III Sandra Pérez Baos promoted to Senior Associate 32 published papers in immunology and molecular biology Scientist. Founder. Investor. In that order Backing biotech from pre-seed to platform acquisition Nucleate New York founding team member PhD in Molecular Biosciences, Universidad Autónoma de Madrid Harvard Business School CORe - Pass with High Honors Investment range $500K - $3M, sweet spot $1.3M Predicting a wave of mid-cap pharma acquisitions in RNA and immunology in 2026
Senior Associate · 2048 Ventures · New York

Sandra
Pérez Baos

The Immunologist Who Writes the Checks

She spent a decade decoding T cells. Now she's decoding founders - and backing the ones who think in pathways.

Ph.D. Biotech VC Seed Stage Nucleate NY Co-Founder HBS CORe High Honors
$82M
Fund III (2026)
32
Published Papers
$1.3M
Sweet Spot Check
10+
Years in Immunology
Sandra Pérez Baos, Ph.D. - Senior Associate at 2048 Ventures

Sandra Pérez Baos was elbow-deep in T-cell mRNA translation at NYU Grossman when she made a decision most scientists don't make: she wanted to be on the other side of the table. Not the bench. The cap table.

That pivot didn't happen overnight, and it didn't happen neatly. It went through Nucleate New York - which she helped build from the ground up as a founding leadership member. It went through NYU's technology commercialization office, where she learned how IP moves from lab to market. And it went through co-founding a therapeutics startup during her own postdoc - experiencing the founder's specific kind of paranoia and momentum before she ever evaluated it in someone else.

Now she's a Senior Associate at 2048 Ventures, a thesis-driven VC firm headquartered in New York with a Boston presence, that just closed Fund III at $82,048,000. (Yes, the $2,048,000 part is intentional. The firm puts its name in the number.) She writes checks between $500K and $3M into pre-seed and seed-stage biotech and health companies - and she's doing it with something most investors at that level simply don't have: a working understanding of what it feels like to be the person asking for the money.

Her scientific background is not decorative. Sandra holds a B.S. in Biotechnology from the University of Salamanca, an M.S. in Immunology from Universidad Complutense de Madrid, and a Ph.D. in Molecular Biosciences from Universidad Autónoma de Madrid. She has published 32 papers. Her postdoctoral research at NYU Grossman zeroed in on translational reprogramming of T cells - the molecular switch between a cell's genetic instructions and its behavior in cancer and autoimmunity. That's not background knowledge. That's the kind of domain depth that lets her see through a data deck in a first meeting.

"For early-stage VCs, the current environment is constructive as pharma shows willingness to buy platform science earlier in the lifecycle to support exits for 2018-2021 vintage companies reaching early clinical validation."
- Sandra Pérez Baos, on the 2026 biotech M&A environment

The investment thesis at 2048 Ventures is built around data moats - the idea that generational companies are the ones that capture proprietary data, turn it into durable insight, and build competitive advantages that compound. In biotech and health, that translates to real-time measurement infrastructure, novel IP, and platform biology that pharma can't easily replicate internally. Sandra's job is to find those companies before they're obvious.

She's watching RNA, cell therapy, molecular degraders, and metabolic biology. She thinks the Q1-2026 acquisition activity by pharma - deals mostly in the $500M-$3B range for platform assets rather than late-stage commercial products - signals something larger: a systematic move by large pharma to reload their pipelines by buying earlier-stage science. That's the context she's investing into. Not the last deal. The next dozen.

She helped launch a therapeutics startup while still completing her postdoctoral fellowship at NYU Grossman School of Medicine. That's not a resume line. That's firsthand experience with fundraising, co-founder dynamics, early hires, and the specific pressure of trying to turn a scientific hypothesis into a company while still running experiments in the lab. She was a founder before she became the person evaluating founders.

Her path from Salamanca to lower Manhattan is the kind of story that sounds like a plan in retrospect but almost certainly wasn't. Three science degrees in Spain. A postdoc in New York. A fellowship at NYU's tech transfer office. A founding role at Nucleate. A startup co-founded on the side. And somewhere in that chain - the pivot. Science to capital. Researcher to investor. Thirty-two papers to a $1.3M average check size.

What makes her unusual in a field that's increasingly credentialed but rarely scientific is the combination: she can read a paper and know if the mechanism is defensible, and she can read a cap table and know if the structure makes sense. That's a rarer skill set than either alone.

At Nucleate New York - the nonprofit that runs biotech entrepreneurship programming and talent development - she served as Mentor Relations Director and Tech Sourcing Lead. That's infrastructure-building work. It means she was thinking about the ecosystem, not just her own career, years before she had capital to deploy. The VCs who end up being most useful to founders are often the ones who were working on the problem before they had a fund.

"If current patterns hold through 2026, there will likely be a steady cadence of mid-cap platform acquisitions rather than mega deals, with immunology and protein/RNA biology remaining high on pharma's shopping list."
- Sandra Pérez Baos, on pharma M&A trends

2048 Ventures itself is a firm that bets on thesis over trend. It identifies structural data advantages - in Vertical AI, Deep Tech, and Healthcare/Biotech - and invests before the category becomes crowded. The portfolio includes GlossGenius, Gorgias, and DataCamp, with an NPS score of 100 from founders across seven consecutive years. For Fund III, the LPs include people from DigitalOcean, Duolingo, Google, MongoDB, Reddit, and Tiger Global. Sandra was promoted to Senior Associate on the fund close in January 2026.

She's one of a new generation of scientist-investors who are changing what early-stage health and biotech investing looks like - not by wearing a lab coat in a board meeting, but by bringing the intellectual rigor of the bench to the judgment calls of the check. The 32 papers are in the past. The next chapter is about which companies she backs, and whether their science turns out to be as defensible as it looked in the pitch.

32 Scientific Papers
3 Science Degrees in Spain
$82M Fund III (2026)
10+ Years Immunology Research
1 Startup Co-Founded
7 Years 100 NPS at 2048

Where She's Looking

Pre-seed and seed across biotech and health - with an eye toward platform biology that pharma will want to buy before it reaches Phase 2.

🧬
Biotechnology
Seed & Pre-seed
💊
Therapeutics
Seed & Pre-seed
🔬
Drug Delivery
Seed & Pre-seed
🩺
Digital Health
Seed & Pre-seed
🧪
Diagnostics
Seed & Pre-seed
💻
Health IT
Seed & Pre-seed
⚗️
Material Science
Seed & Pre-seed
🧫
Pharmaceuticals
Seed & Pre-seed
RNA Biology Cell Therapy Molecular Degraders Immunology Metabolic Biology Protein Biology Platform Science Data Moats

From Bench to Cap Table

Spain
B.S. Biotechnology at Universidad de Salamanca - the foundation. Three degrees would follow across three Spanish universities.
Madrid
M.S. in Immunology at Universidad Complutense de Madrid - specializing in the molecular machinery of the immune system.
Madrid
Ph.D. in Molecular Biosciences at Universidad Autónoma de Madrid - the decade-long scientific foundation begins here.
2019
Postdoctoral Research Scientist at NYU Grossman School of Medicine. Research focus: T cell mRNA translation, therapeutic approaches to cancer and autoimmunity.
2021-23
Founding leadership team at Nucleate New York. Mentor Relations Director and Tech Sourcing Lead. Building the infrastructure for the NYC biotech entrepreneur ecosystem.
2022-23
Business Development Fellow at NYU Technology Opportunities and Ventures (TOV). Learning how scientific IP moves from lab to licensee to company.
2023
Co-founded a therapeutics startup during postdoc. Still running experiments. Already building a company. The overlap was intentional.
2023
Joined 2048 Ventures as part of the biotech and health investment team. NYC + Boston. Thesis-driven. Data moats.
Jan 2026
Promoted to Senior Associate. 2048 Ventures closes Fund III at exactly $82,048,000 - oversubscribed, with LPs from DigitalOcean, Duolingo, Google, MongoDB, Reddit, and Tiger Global.
Education
  • 🎓
    Ph.D. in Molecular Biosciences
    Universidad Autónoma de Madrid
  • 🔬
    M.S. in Immunology
    Universidad Complutense de Madrid
  • 🧬
    B.S. in Biotechnology
    Universidad de Salamanca, Spain
  • 🏛️
    CORe Credential - Pass with High Honors
    Harvard Business School Online
Research Expertise
Flow Cytometry Immunohistochemistry Primary Cell Culture Immunoblotting T Cell Biology mRNA Translation Autoimmunity Cancer Immunology

Things Worth Knowing

32
Published scientific papers in immunology and molecular biology. That's 32 more than most people writing biotech checks at the seed stage.
$82M
The fund amount isn't rounded - it's exactly $82,048,000. The firm's name is baked into every check they write.
3
Science degrees, all from Spanish universities - Salamanca, Complutense de Madrid, and Autónoma de Madrid - before she moved to New York for her postdoc.
1st
She was part of the founding leadership team at Nucleate New York, helping build the biotech entrepreneur network before she ever had capital to deploy.
HBS
Harvard Business School CORe credential completed with Pass with High Honors - the business layer added on top of a decade of hard science.