Cancer care that never leaves your side - in the home, on the phone, and in the long hours between appointments.
It's a Tuesday night, well after the clinic has locked up. A woman three weeks into chemotherapy is staring at a fever she doesn't understand and a phone she isn't sure she's allowed to use. This is the moment Daymark Health was built for - the gap between appointments, where most of cancer actually happens.
Daymark Health is a Philadelphia-based cancer care company that does something quietly radical: it shows up when the oncologist's office is closed. Through a hybrid of in-home visits and virtual care, its team of nurse practitioners, nurses, licensed clinical social workers, and health navigators handles symptoms, side effects, anxiety, and the logistics of getting to treatment. It works alongside a patient's existing oncologist, not instead of them.
Pictured in spirit: the 8,500 hours a year a cancer patient spends outside the clinic. Daymark wants the receipts for all of them.
"We built Daymark Health to provide compassionate, intelligent, and frictionless cancer care at scale."
- Dr. Justin Bekelman, CEO & Co-FounderRoughly two million Americans are diagnosed with cancer every year. They get superb care during their appointments - and then they go home, where the system mostly stops. By Daymark's own estimate, patients spend more than 8,500 hours a year outside the oncology clinic. Those are the hours when a manageable side effect becomes an ER visit, when the fear sets in, when the ride to treatment falls through.
The care is fragmented. The support is thin. And the cost of all those avoidable crises lands on patients, providers, and health plans alike. It's an inconvenient arrangement that everyone has agreed to tolerate for a remarkably long time.
Symptoms and side effects surface at home, hours from a clinician who knows the case.
Anxiety, depression, and caregiver strain rarely get a dedicated phone number.
Transportation, money, and housing quietly decide whether treatment happens at all.
The hardest part of cancer is rarely the appointment. It's everything that happens between them.
- The Daymark thesis, paraphrasedDaymark was built out of the venture studio Healthcare Foundry and led by Dr. Justin Bekelman, who previously ran Penn Medicine's Center for Cancer Care Innovation at the Abramson Cancer Center. He'd spent a career watching the clinic do its job well and the hours around it do nothing at all. Co-founders Robert Pahlavan and Jonathan Rhodes helped shape the thesis.
The bet was structural, not sentimental. Instead of selling a feel-good service, Daymark would partner with health plans and take on risk for the total cost of cancer care - betting that better support between appointments would mean fewer emergencies, and that the savings would more than pay for the care. Compassion, it turns out, can also be a business model.
Also on the bench: former Humana CMO Roy Beveridge (Executive Board Chair) and ACA architect Ezekiel Emanuel (Clinical Advisory Board Chair). Not a lineup you assemble by accident.
The thesis takes shape inside a venture studio: supportive cancer care delivered where patients actually live.
Co-led by Maverick Ventures and Yosemite, with Oncology Ventures. Operations begin with a Northeast health plan partner.
The hybrid in-home and virtual model scales across a growing roster of plan members.
Led by Healthier Capital and the Blue Venture Fund, with existing investors returning. Total raised reaches $31.5M.
Daymark's supportive cancer care program reaches patients by phone, text, video, and home visit. Behind the friendly front door sits a multidisciplinary team and a technology platform doing five things at once:
Coordinating appointments, screening, and diagnosis through a maze most patients face alone.
Round-the-clock management of side effects before they become 2 a.m. emergencies.
Behavioral support from licensed clinical social workers, for patients and caregivers.
Transportation, financial help, housing - the practical barriers to staying in treatment.
Everything shared back to the patient's own oncologist, so nobody flies blind.
It is, essentially, the friend who happens to be an oncology nurse - except this one answers at midnight and files the paperwork.
"Daymark is delivering a transformational model of personalized, high-quality, value-based cancer care."
- Dr. Aman Mahajan, Healthier CapitalWithin its first year of operations, Daymark grew to support more than 2,500 cancer patients, starting with a Northeast health plan and expanding through partnerships including Blue Cross & Blue Shield of Rhode Island. Investors followed the patients: a $11.5M seed in April 2025 and a $20M Series A in September 2025.
Source: Daymark Health press releases, Apr & Sep 2025. Bars scaled to the $20M round.
Two rounds in six months. The cancer-care market is enormous; the patience of its patients is not.
"We're thrilled to partner with Daymark as they redefine the cancer care experience."
- Kelsey Maguire, Blue Venture FundDaymark frames its mission around three audiences at once: patients who need support to live through treatment, providers who can't be everywhere, and health plans looking to spend on care that actually works. Its job is to deliver evidence-based supportive care that handles the clinical, mental health, and social needs that traditional oncology was never built to reach.
The value-based structure keeps everyone honest. Daymark only wins when patients have fewer crises - which means the incentive and the mission point in the same direction. A pleasant novelty in healthcare.
With fresh capital, Daymark plans to forge new partnerships with health plans and providers across the country and bring its platform to more patients. Two million new diagnoses a year, multiplied by 8,500 unattended hours each, is a problem large enough to absorb far more than one company - and specific enough that getting it right would change what a cancer diagnosis feels like.
Back to that Tuesday night. The woman with the fever picks up her phone. Someone answers - an oncology nurse who knows her name, her treatment, and exactly what to do next. No drive to the ER. No guessing. The clinic closed hours ago, but the care didn't. That's the change Daymark is selling, and increasingly, the one it's delivering.