vt-5006
(2)
Vertero Therapeutics, Inc.
Vertero Therapeutics is a clinical-stage biotechnology company in Woburn, Massachusetts, developing oral small-molecule drugs for neurodegenerative diseases by targeting causative drivers in the body's periphery - primarily the gut - rather than only the brain. Formerly Axial Therapeutics, the company rebranded as Vertero in October 2025. Its lead candidate, VT-5006, is a gut-selective small molecule for Parkinson's disease that targets CsgA, a bacterial protein linked to protein aggregation and neuroinflammation, and is entering Phase 1 trials.
Stewart Campbell
A. Stewart Campbell, PhD, is the CEO of Vertero Therapeutics, the Woburn, Massachusetts biotech formerly known as Axial Therapeutics. A medicinal chemist by training with more than 30 years in drug discovery, he runs a company built on an unusual bet: that the road to treating Parkinson's disease starts in the gut, not the brain. Campbell joined in 2017, took the top job in February 2021, engineered the 2025 rebrand from Axial to Vertero, and is steering the lead candidate VT-5006, a gut-selective small molecule, into its first clinical trials. He is a co-inventor on more than 20 patent families, including the foundational patents behind the approved graft-versus-host disease drug Rezurock.