systemic-lupus-erythematosus
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Resolve Therapeutics Missed the Headline Endpoint - Then Built a Smarter Trial From the Miss
The tiny Miami biotech spent years testing a simple idea: digest inflammatory RNA instead of suppressing the immune system. Its first big readouts were messy - and the useful part was hiding inside the miss.
Progentec Diagnostics, Inc.
Progentec Diagnostics is an Oklahoma City company building blood-based biomarker tests and digital health tools for autoimmune diseases, starting with lupus. Its lead product, the aiSLE DX Flare Risk Index, uses an 11-biomarker algorithm to predict a lupus flare up to 12 weeks before it happens, giving rheumatologists a chance to intervene early. Spun out of research tied to the Oklahoma Medical Research Foundation, the company pairs lab science with patient-facing tools like the LupusCorner community to move autoimmune care from reactive to proactive.