Sanavia Oncology is a New York-based biotech company developing next-generation cancer immunotherapies for patients who don't benefit from existing treatments. Its proprietary platform pairs high-throughput sequencing, single-molecule super-resolution microscopy, 3D protein modeling and artificial intelligence to discover novel, clinically relevant cancer-specific epitopes in drug-resistant tumors, then generates antibodies with atomic-level specificity to those targets. The company is building antibody drug conjugates (ADCs), bispecific T cell engagers (TCEs) and CAR-T therapies - led by its SANA-01 ADC - and is backed by Two Bear Capital.
ONI (Oxford Nanoimaging) is an Oxford University spinout that shrank the super-resolution microscope from a room-sized, six-figure instrument into a desktop box the size of a sheet of A4 paper. Its flagship Nanoimager resolves single molecules down to 20 nm and pairs with the cloud-based CODI platform for analysis and collaboration, opening single-molecule science to labs studying everything from extracellular vesicles to lipid nanoparticles and cancer.