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Vol. II — No. 184Remarkable People · Exceptional CompaniesToday's Edition

shape-memory-alloy

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Company
The Tiny Motor That Taught a Doll to Blink
Hardware · Enterprise · Consumer

The Tiny Motor That Taught a Doll to Blink

NanoMuscle made metal wire move like muscle. A blinking doll revealed the promise - and the maddening precision - of turning that trick into a product.

nanomuscle · shape-memory-alloyRead →
Company
Zenflow, Inc.
Health · Hardware · Enterprise

Zenflow, Inc.

Zenflow is a South San Francisco medical device company that built the Spring, a small nitinol coil implanted through a flexible cystoscope to prop open the urethra and relieve the symptoms of an enlarged prostate (benign prostatic hyperplasia). Spun out of Stanford's Biodesign program in 2014, the company won FDA approval in December 2025 for a first-line interventional therapy that requires no catheter afterward, preserves sexual function, and can be reversed. It has raised roughly $85 million across multiple rounds and ran the multinational BREEZE pivotal trial to get there.

medical-devices · bphRead →