Omphalos Lifesciences is a Dallas-based biotech software company building a programmable virtual cell platform. Founded by computational biologist Daehwan Kim - creator of the widely used HISAT and TopHat sequencing tools - the company created L++, a high-level programming language that lets biologists describe, simulate, and visualize living systems the way software engineers write code. Its Life Designer platform aims to accelerate drug discovery, precision medicine, and biomanufacturing by running experiments in silico before they hit the lab bench.
Profluent is an AI-first protein design company building frontier models that author novel proteins - including the first AI-designed CRISPR gene editor, OpenCRISPR-1. Based in Berkeley's biotech corridor, the company applies the same scaling-law playbook that worked for language models to the language of biology, then validates the outputs in a wet lab.