Some proteins are difficult to block. Dewpoint is testing whether changing where they gather inside a cell can change what they do - and its first cancer drug has reached patients.
A pill can change brain chemistry. Remepy is testing whether a phone can help change what happens next - and whether the two belong on the same prescription.
Dualitas is betting that the most useful thing an antibody can do is not merely bind twice, but force the right two proteins into the same conversation. Roche just paid $36.5 million upfront to test that idea at industrial scale.
How a group-buying network built by former pharma executives quietly became the largest independent community-oncology network in the country - and why staying small and independent is the whole point.