From a Depression-era yogurt counter in Pittsburgh to a global supplement empire of roughly 14,000 people, GNC keeps rewriting the same question: what does a vitamin store look like when the customer shops on their phone?
Imagene Labs is a Singapore-based health-tech company that runs an enterprise-grade, cloud-based B2B genetic analytics platform. Using patented ancestry-based genetic risk analytics and ethnically-relevant reference datasets, it turns a simple saliva sample into DNA insights that fitness, beauty, nutrition and healthcare brands use to build personalized products and services. Its consumer-facing brand, Ori, packages these insights into fitness, skincare and nutrition DNA tests for the Asian market and beyond.
InsideTracker is a Cambridge, Massachusetts personalized health and wellness company (legally Segterra, Inc.) that turns your blood, DNA, and wearable data into a science-backed action plan. Founded in 2009 by MIT-trained scientist Dr. Gil Blander, the platform analyzes dozens of blood biomarkers, estimates your biological 'InnerAge,' and recommends specific foods, supplements, and lifestyle changes to optimize performance, healthspan, and longevity. It has become a favorite of athletes and quantified-self enthusiasts and integrates directly with Garmin, Fitbit, Oura, and Apple devices.
Gainful is a New York-based personalized sports nutrition company that builds custom protein powders, hydration, pre-workout and performance supplements tailored to each customer's body, goals and dietary needs. Customers take an online quiz, get a formula matched to them by Gainful's algorithm and registered dietitians, and can chat with a real RD about it. Founded by high-school soccer teammates Eric Wu and Jahaan Ansari and incubated at Y Combinator, the brand grew from a dorm-room experiment into a profitable, multi-channel business now sold direct-to-consumer and in Target stores nationwide.
Biohm Technologies is a Cleveland-based microbiome innovation company that studies the gut as a whole - bacteria and fungi together - rather than bacteria alone. Built on 40+ years of fungal research by Dr. Mahmoud Ghannoum, the scientist who named the mycobiome, Biohm develops data-driven biotic ingredients and gut-health testing solutions. Its flagship ingredient Mycohsa is the first probiotic blend clinically shown to break down digestive biofilms, and its Symbiont discovery platform mines a large bacterial-fungal dataset to design targeted microbiome products. After a B2B pivot in 2024, the company now sells ingredients and microbiome science to nutraceutical and food brands.