off-the-shelf-cell-therapy
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John Lu
Shi-Jiang (John) Lu is a stem cell scientist and the founder, President and CEO of HebeCell Corp, a Natick, Massachusetts biotech building off-the-shelf cancer-killing immune cells from pluripotent stem cells. He spent two decades in regenerative medicine, was a top-ranked inventor in the global stem cell patent landscape, and led research at Advanced Cell Technology before that company was absorbed by Astellas. At HebeCell he pioneered a 3D, feeder-free bioreactor process for growing iPSC-derived natural killer (NK) and CAR-NK cells at industrial scale - aiming to make potent immune therapies as standardized and reproducible as a manufactured product.
Rachel Haurwitz
Rachel Haurwitz is the President and CEO of Caribou Biosciences, a clinical-stage biopharmaceutical company she co-founded in 2011 with Nobel laureate Jennifer Doudna and colleagues Martin Jinek and James Berger. A pioneer in CRISPR commercialization, Haurwitz earned her PhD from UC Berkeley under Doudna's mentorship — she was the first student in the lab to work on CRISPR — and pivoted from academia to industry to bring genome-editing technology to patients. Under her leadership, Caribou has developed a proprietary Cas12a-based platform (chRDNA technology) enabling precise, multiplex genome editing for off-the-shelf allogeneic CAR-T and CAR-NK cell therapies targeting blood cancers and autoimmune diseases. She also co-founded Intellia Therapeutics in 2014 and has been recognized on Forbes 30 Under 30, Fortune 40 Under 40, and featured in Walter Isaacson's bestseller 'The Code Breaker.'