J. Eduardo Rame

J. Eduardo Rame is a Philadelphia cardiologist who treats the sickest hearts in medicine - patients in the final stage of heart failure who depend on pumps, transplants and the chance their own muscle can be coaxed back to life. As the Louis R. Dinon MD Professor and enterprise chief of Advanced Cardiac and Pulmonary Vascular Disease at Jefferson Health, he runs an integrated division built around recovery rather than replacement. Yale-trained in biophysics, Oxford-trained in health economics and Harvard-trained in medicine, he spent a decade founding Penn's mechanical circulatory support program before bringing that work to Jefferson. His research on left ventricular assist devices, including the landmark MOMENTUM 3 trial, has been cited more than 12,000 times.