Shaped is a New York-based AI company that builds a real-time relevance engine for recommendations, search, and agent retrieval. Its managed platform, Shaped Cloud, combines embeddings, machine-learning models, and fresh behavioral data to return personalized results in under 50 milliseconds, letting product and engineering teams add for-you feeds, hybrid search, and personalized discovery without building ranking infrastructure from scratch. Founded in 2021 by Tullie Murrell, Daniel Camilleri, and Shai Bruhis, the company raised an $8M Series A led by Madrona in 2024 and was acquired by live-commerce marketplace Whatnot in July 2026.
Impart Security is a San Francisco cybersecurity company building a unified runtime protection platform for AI, APIs, and web applications. Founded in 2020 by Signal Sciences veterans Jonathan DiVincenzo, Marc Harrison, and Brian Joe, the company merges WAF, API security, Cloud Application Detection & Response, and AI Runtime Protection into one engine that runs autonomous defense agents inside production traffic.
Ajay Kshatriya is the CEO and co-founder of Aizen Therapeutics, a San Diego biotech that spun out of Caltech to build 'Mirror Peptides' - drugs made entirely of D-amino acids, the mirror image of the proteins nature uses. The company launched from stealth in November 2024 with $13M and a generative-AI platform called DaX. Before Aizen, Ajay founded and ran Biota, an environmental genomics company acquired by Novozymes in 2021 after creating roughly $400M in economic value and saving 1.2 billion gallons of water for industrial clients. A UC Berkeley and Stanford-trained chemical engineer who began his career at Genentech and learned company-building as a seed investor at XSeed Capital, he now also invests in Caltech science startups as a partner at Wilson Hill Ventures.
Dilpreet Sahota is the co-founder and CEO of Trek Health, a San Mateo-based, AI-powered platform that turns the federal price-transparency data dump into a weapon healthcare providers can use to benchmark and negotiate their payer contracts. Founded in January 2022, Trek Health landed its first paying customer two months later, crossed 100 customers by late 2024, and raised an $11M Series A led by Madrona in 2025. A Stanford and UC Berkeley graduate who cut his teeth at Health IQ and Big Health, Sahota built Trek to attack a quietly brutal problem: identical medical services can be reimbursed at rates that vary 300-500%, and the smaller players almost never know it.
Doug Tallmadge is the co-founder and CEO of Gradial, a Seattle enterprise-AI company building agentic tools that automate the unglamorous middle of marketing - the approvals, tagging, compliance checks, and publishing that sit between a finished idea and a live campaign. Before Gradial, he spent nearly five years at SpaceX as a software engineering manager, where he helped scale the Starlink network from zero to more than 500,000 customers. A Dartmouth physics graduate who also passed through Lockheed Martin and Bridgewater Associates, he started Gradial in 2023 with three Dartmouth classmates and has since raised roughly $53M across seed, Series A, and a $35M Series B led by VMG Partners.
Harley Sugarman is the founder and CEO of Anagram, a New York security company rebuilding employee security training around behavior instead of boredom. A Stanford computer scientist and former Bloomberg Beta investor, he scrapped his original product and rebuilt it into a TikTok- and Duolingo-inspired microlearning platform that cut client phishing failure rates from 20% to 6% and won over Disney, Thomson Reuters, and MassMutual. Anagram raised a $10M Series A in 2025 led by Madrona.