machine-learning-biotech
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Weston Kightlinger
Weston Kightlinger is the CEO and co-founder of Ridge Bio (Ridge Biotechnologies), a Palo Alto biotech that left stealth in September 2025 with $25 million in seed funding to design precision enzymes and targeted therapeutics by pairing machine learning with massive cell-free laboratory datasets. A Northwestern-trained scientist with a background in cell-free protein synthesis and protein glycosylation, he turned a decade of bench work into a company whose advisory board reads like a who's-who of chemical biology, including Nobel laureate Carolyn Bertozzi.
Jacob Borrajo
Jacob Borrajo is the Founder and CEO of Amber Bio, a Cambridge-based biotech company pioneering a first-of-its-kind RNA writing platform capable of multi-kilobase edits. With a PhD in Biological Engineering from MIT and research training at the Broad Institute, Borrajo has spent his career building at the intersection of CRISPR, machine learning, and synthetic biology. Amber Bio launched in August 2023 with a $26 million seed round co-led by Andreessen Horowitz and Playground Global, with strategic participation from Eli Lilly and the Retinal Degeneration Fund. His platform's key innovation: treating diseases with high allelic diversity using a single therapeutic product, by editing RNA rather than DNA - making gene therapy safer, reversible, and dramatically more scalable.