Apreo Health is a clinical-stage medical device company in Menlo Park, California developing the BREATHE Airway Scaffold, a bronchoscopically delivered, self-expanding nitinol implant that relieves lung hyperinflation in patients with severe emphysema. Unlike existing valve and surgical treatments that collapse or remove lung tissue, the scaffold gently tents open damaged airways to release trapped air while sparing healthy tissue, aiming to expand who can be treated. The company raised a $130M Series B in August 2025 to run its pivotal BREATHE-3 trial and prepare for early commercialization.
Nob Hill Therapeutics is an Albuquerque, New Mexico respiratory healthcare company re-envisioning inhalation medicines. Its patented DryNeb dry powder nebulizer is designed to deliver high doses of medicine directly to the lungs while a patient breathes normally, combining the strengths of dry powder inhalers and liquid nebulizers. Spun out of VIC Technology Venture Development and based on the Lovelace Respiratory Research Institute campus, the company is targeting hard-to-treat lung diseases such as lower respiratory tract infections, lung fungal infections and lung cancer.