Kira Biotech is a Brisbane-based clinical-stage immunology company developing first-in-class antibody therapeutics that retrain the immune system instead of broadly suppressing it. Its lead candidate, KB312, selectively depletes activated immune cells to restore immune tolerance, aiming to treat difficult autoimmune and inflammatory conditions such as rheumatoid arthritis, lupus, type 1 diabetes, and graft-versus-host disease. Built on decades of dendritic-cell research from Australian institutes and led by US rheumatologist Dr Dan Baker, the company launched with a A$20 million Series A in 2019 led by OneVentures and IP Group.
Dan Baker is a physician-scientist turned biotech founder who spent two decades at Johnson & Johnson's Janssen division helping bring immunology blockbusters Remicade, Simponi and Stelara to patients, before launching Brisbane-based Kira Biotech in 2019 as its founding CEO. Kira is developing KB312, a first-in-class antibody designed to selectively retrain the immune system rather than broadly suppress it, aimed at autoimmune diseases such as rheumatoid arthritis, lupus and type 1 diabetes. A rheumatologist who taught at the University of Pennsylvania for 18 years, Baker also advises drug-development organisations and serves as a healthcare venture partner.