Aera Therapeutics is a Cambridge, Massachusetts biotech founded on a discovery from CRISPR pioneer Feng Zhang: human proteins that can self-assemble into capsid-like shells and ferry genetic cargo into cells. The company is building delivery platforms - protein nanoparticles, targeted lipid nanoparticles, and antibody-oligonucleotide conjugates - to solve the field's most stubborn problem: getting genetic medicines to the right tissue. Launched publicly in 2023 with $193M and led by Alnylam veteran Akin Akinc, Aera is betting that delivery, not the drug itself, is the bottleneck holding back the next generation of genetic medicine.
Moonwalk Biosciences is a San Francisco Bay Area biotech building precision epigenetic medicines. Co-founded by former Illumina CTO Alex Aravanis and CRISPR pioneer Feng Zhang, the company pairs whole-genome, single-cell epigenome mapping with AI-guided 'read-and-write' epigenetic editing tools that reprogram cells to a healthy state without cutting or altering the underlying DNA. Launched out of stealth in January 2024 with $57 million in seed and Series A funding, Moonwalk aims to file its first IND within a few years.