edc
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THREAD Moved the Clinical Trial to the Patient's Kitchen Table
For decades a clinical trial meant a patient driving to a site. THREAD bet the visit could come to them instead - and then bought four companies to prove it.
The Company Teaching Drug Trials to Stop Drowning in Their Own Data
A clinical trial can generate data from a hundred different sources. eClinical Solutions built the plumbing to make it all speak the same language - and now it is handing the busywork to AI agents.
Blade HQ
Blade HQ is an online and brick-and-mortar knife retailer founded in 2003, offering thousands of pocket knives, tactical and outdoor blades, multitools, flashlights, and everyday-carry (EDC) gear from top brands like Benchmade, Spyderco, CRKT, Kershaw, and Microtech. Based in Utah with a second location in Marion, Virginia, the company is known for its enormous in-stock selection, Blade HQ Exclusives (limited-edition and collaboration knives made only for its customers), the Blade Club rewards program, and its long-running Knife Life content and video channels that have helped grow the modern EDC community.
Castor
Castor is a health-technology company that builds a cloud-based eClinical platform for running clinical trials - from electronic data capture (EDC) and eConsent to eCOA/ePRO and real-world evidence. Founded in 2012 in Amsterdam by physician-researcher Dr. Derk Arts, Castor set out to replace clunky, expensive trial software with a self-service, researcher-friendly system. Today it supports more than 15,000 studies across 90+ countries and is used by leading CROs and biopharma companies, while pushing decentralized trials and practical AI (Castor Catalyst, built with Google Cloud) into mainstream research.
ClinCapture
ClinCapture is an eClinical software company that builds cloud-based tools for running clinical trials - electronic data capture (EDC), ePRO/eCOA, eConsent, randomization, medical coding, and trial master file management. Born from consulting firm Clinovo and once known as the only free, fully validated open-source EDC in the world, it now markets a unified, AI-augmented platform called Captivate that lets sponsors and CROs design, launch, and manage studies from a single validated cloud system.
Curebase
Curebase is a San Francisco-based eClinical software company building an AI-powered platform that runs clinical trials around patients' lives instead of inside hospital walls. Its single system spans study startup to database lock - combining electronic data capture (EDC), eConsent, ePRO/eCOA, patient recruitment, and a virtual research site model - so sponsors can launch decentralized and hybrid trials faster, capture cleaner data, and reach more diverse participant populations.
Medrio
Medrio is a San Francisco-based eClinical software company that helps pharma, biotech, medtech and diagnostics teams run clinical trials with a no-code, cloud-based EDC, eCOA/ePRO, eConsent and RTSM suite. Founded in 2005 and bootstrapped for more than a decade before taking outside capital, Medrio now powers thousands of studies across four continents.