decentralized-trials
(6)
The Doctor Who Built a Research Machine Because He Never Had Time to Do Research
Dr Matt Wilson spent 14-hour shifts in emergency medicine with no time to eat, let alone run a study. So he built a platform that makes the research happen without the clinician lifting a finger - and pharma is paying to plug in.
ClinCapture
ClinCapture is an eClinical software company that builds cloud-based tools for running clinical trials - electronic data capture (EDC), ePRO/eCOA, eConsent, randomization, medical coding, and trial master file management. Born from consulting firm Clinovo and once known as the only free, fully validated open-source EDC in the world, it now markets a unified, AI-augmented platform called Captivate that lets sponsors and CROs design, launch, and manage studies from a single validated cloud system.
Medeloop
Medeloop is an AI-powered clinical research platform building an operating system for medical evidence - from grant discovery to real-world evidence generation to point-of-care intelligence. Founded by former surgeon Dr. Rene Caissie, the San Francisco company uses agentic AI to automate biostatistics, study monitoring, and protocol compliance for academic medical centers, health systems, and pharma.
NuvoAir Medical
NuvoAir Medical is a virtual-first cardiopulmonary care company that helps patients with chronic heart and lung conditions - COPD, asthma, and CHF - manage their health from home before they end up in a hospital. Founded in Stockholm in 2015-2016 by Lorenzo Consoli and now headquartered in Boston, NuvoAir pairs FDA-cleared connected devices like the Air Next home spirometer with a clinical care team and data-driven monitoring. Its model is built around value-based care, with studies showing meaningful reductions in medical spend and hospitalizations. The company also powers decentralized clinical trials for pharma partners.
xCures Inc.
xCures is an AI-powered health-data platform that automatically retrieves medical records from any care site in the United States, then structures, normalizes, and validates that messy, unstructured data into searchable, source-traceable clinical insights. Born in oncology, it generates regulatory-grade real-world evidence, AI-built clinical checklists, and natural-language patient summaries that help researchers, biopharma, advocacy groups, and clinicians understand each patient's full medical journey - and run continuously learning 'virtual trials' across all patients, all treatments, all the time.
Medrio
Medrio is a San Francisco-based eClinical software company that helps pharma, biotech, medtech and diagnostics teams run clinical trials with a no-code, cloud-based EDC, eCOA/ePRO, eConsent and RTSM suite. Founded in 2005 and bootstrapped for more than a decade before taking outside capital, Medrio now powers thousands of studies across four continents.