dapansutrile
(2)
Olatec Therapeutics
Olatec Therapeutics is a clinical-stage biopharmaceutical company in New York developing a platform of oral NLRP3 inflammasome inhibitors to treat acute and chronic inflammatory diseases. Its lead compound, dapansutrile (OLT1177), is a selective small-molecule NLRP3 inhibitor that has shown clinical benefit and a clean safety profile across gout, heart failure and a broad range of inflammatory and neuroinflammatory conditions, positioning oral inflammasome blockade as a potential alternative to injectable IL-1 biologics.
Damaris Skouras
Damaris Skouras is the founder, chairman, and CEO of Olatec Therapeutics, a New York clinical-stage biopharmaceutical company built around dapansutrile, an oral, specific NLRP3 inflammasome inhibitor she has pushed from the lab bench into Phase 2 trials spanning gout, melanoma, type 2 diabetes, and Parkinson's disease. She started in finance as a Wall Street biotech banker in 1982, founded her own investment advisory firm in 1985, and eventually crossed the table to run the kind of company she used to finance. With a Stanford degree, a Harvard MBA, and the immunologist who discovered interleukin-1 as her co-founder, she has raised over $100 million to bet that a single inflammatory switch can be turned off across a range of diseases.