critical-care
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The Startup Teaching Ventilator Patients to Breathe on Their Own Again
Every long stint on a ventilator quietly weakens the one muscle you need to breathe. XN Health's Phlex device stimulates the phrenic nerve through the breathing tube to keep the diaphragm working - and get patients off the machine sooner.
Inflammatix, Inc.
Inflammatix is a Sunnyvale, California molecular diagnostics company that reads the body's own immune response instead of hunting for the pathogen. Its FDA-cleared TriVerity test measures 29 host mRNAs from a blood sample and, using machine-learning algorithms, returns three scores in about 30 minutes: likelihood of bacterial infection, likelihood of viral infection, and overall illness severity. Run on the company's benchtop Myrna instrument, it is built for emergency and critical-care clinicians who need to decide fast whether a patient is heading toward sepsis. Spun out of Stanford in 2016, the company has raised more than $205M.
ImaCor, Inc.
ImaCor, Inc. is a New York medical-device company that built the world's first and only hemodynamic transesophageal echocardiography (hTEE) platform for the intensive care unit. Its miniaturized, disposable ClariTEE probe can stay safely in a critically ill patient for up to 72 hours, giving clinicians a continuous, direct window onto the heart - preload, contractility, and right- and left-ventricular function - so they can guide fluids and drugs in real time instead of guessing. In 2022 ImaCor and Clarius Mobile Health launched the FDA-cleared Zura Handheld Hemodynamic Ultrasound, a pocket-sized, 22-ounce TEE system that puts that window in a clinician's hand.
Vituity
Vituity is a 100% physician-owned and led multispecialty partnership delivering acute care across the United States. Founded in 1971 as California Emergency Physicians (CEP America), it rebranded as Vituity in 2018, combining 'vital' and 'acuity.' Today roughly 5,500 doctors and clinicians staff emergency departments, hospital medicine, critical care, anesthesiology, psychiatry, neurology, telehealth and more across hundreds of care sites in 27+ states, treating millions of patients a year - all without private equity, insurer, or hospital-system ownership.