cancer-therapy

(5)
Legend
Filippo Petti
Executive · Operator · Scientist

Filippo Petti

Filippo Petti is the Chief Executive Officer of Leucid Bio, a London-based clinical-stage biotech developing next-generation CAR-T cell therapies for solid tumours built on a proprietary lateral CAR platform spun out of two decades of King's College London research. Appointed CEO in July 2023, Petti pairs a bench-science start at OSI Pharmaceuticals with years on Wall Street as a healthcare investment banker and equity analyst, and a prior run leading Celyad Oncology as CEO and CFO. Under his watch, Leucid moved its lead asset LEU011 into the AERIAL Phase I/IIa trial, reporting early proof-of-concept in relapsed/refractory solid tumours in late 2025.

filippo-petti · leucid-bioRead →
Legend
David Earp
Executive · Operator · Founder

David Earp

David J. Earp is the President and CEO of Circle Pharma, a South San Francisco clinical-stage biopharmaceutical company building orally available macrocycle drugs aimed at cancer targets long deemed undruggable. A biochemist turned patent lawyer turned chief executive, Earp holds a PhD in biochemistry from Cambridge and a JD from Lewis & Clark, and has led Circle since 2013, steering it through a $90M Series D, a $607M collaboration with Boehringer Ingelheim, and the first human dosing of its lead cyclin A/B inhibitor CID-078.

david-earp · circle-pharmaRead →
Legend
Jeffrey Stafford
Founder · Executive · Scientist

Jeffrey Stafford

Jeffrey Stafford is the CEO and co-founder of 858 Therapeutics, a San Diego clinical-stage biotech developing small-molecule cancer drugs against novel targets in DNA-damage repair, innate immunity and RNA epigenetics. A chemist by training, he has spent three decades turning molecules into medicines: his discovery teams contributed to three FDA-approved drugs, and he previously led Jecure Therapeutics (acquired by Genentech in 2018) and co-founded Quanticel Pharmaceuticals (acquired by Celgene in 2015). 858's lead asset, the PARG inhibitor ETX-19477, won FDA Fast Track status and posted a 57% response rate in BRCA-mutated ovarian cancer at ASCO 2026.

jeffrey-stafford · 858-therapeuticsRead →
Legend
Jennifer Cygan
Executive · Operator · Advisor

Jennifer Cygan

Jennifer Cygan is a seasoned biotech executive and Chief Business Officer at EpiBiologics, where she helps advance a pipeline of novel bispecific antibodies designed to selectively degrade extracellular protein targets in oncology and immunology. With a Ph.D. from Harvard and over two decades of business leadership in biotechnology, she has been a pivotal force at Genentech, Calico Life Sciences (managing a $2.5B AbbVie alliance), and has co-founded and served as CBO for multiple emerging biotech companies including Broadwing Bio, Eikon Therapeutics, GenEdit, and Plexium. Her career sits at the intersection of science and strategy - translating cutting-edge biology into deals, partnerships, and companies that matter.

biotechnology · biopharmaceuticalsRead →
Legend
Andre Esteva
Founder · Executive · Scientist

Andre Esteva

Andre Esteva, PhD, is the co-founder and CEO of ArteraAI, a medical AI company whose test for personalizing prostate cancer therapy is included in NCCN clinical guidelines, reimbursed by Medicare, and deployed internationally. A Stanford-trained AI scientist whose Nature cover paper first demonstrated that AI could match dermatologists at diagnosing skin cancer, Esteva has co-founded four companies with a combined market cap of $2.2B. Named to TIME100 Health 2025 and Modern Healthcare's 40 Under 40 for 2025, he leads a company that raised $175M total and was named a TIME 2024 Best Invention.

ai · oncologyRead →