Sanuj Ravindran, M.D., is the CEO of Simcha Therapeutics, a New Haven clinical-stage immunobiology company turning a once-overlooked immune molecule, interleukin-18, into a cancer weapon. A board-certified physician who spent a decade as a venture capitalist before becoming a serial biotech company-builder, Ravindran took the helm in 2022 to push ST-067, a decoy-resistant IL-18 designed to slip past the body's own off-switch and reawaken the immune system inside tumors. He has run drug programs across oncology and rare disease, structured more than $2 billion in deals, and bets his career on therapies that promise more than incremental gains.

Shafique Virani is a neurosurgeon-turned-biotech dealmaker who serves as Chief Business Officer of Noetik, an AI-native cancer therapeutics company in South San Francisco. He has spent two decades turning early-stage science into landmark partnerships, including one of the largest drug discovery deals ever struck at Recursion, and earlier built a neuroscience and rare-disease portfolio at Roche/Genentech that produced approved medicines like Risdiplam and Enspryng. At Noetik he is selling a new idea to pharma: not AI services, but licensable AI infrastructure for biology.