Zenflow is a South San Francisco medical device company that built the Spring, a small nitinol coil implanted through a flexible cystoscope to prop open the urethra and relieve the symptoms of an enlarged prostate (benign prostatic hyperplasia). Spun out of Stanford's Biodesign program in 2014, the company won FDA approval in December 2025 for a first-line interventional therapy that requires no catheter afterward, preserves sexual function, and can be reversed. It has raised roughly $85 million across multiple rounds and ran the multinational BREEZE pivotal trial to get there.
Dr. Prithipal S. Sethi is a board-certified urologist, founder and CEO of Golden State Urology, and Chief Medical Officer at Promaxo - the company pioneering in-office MRI technology for prostate cancer diagnosis and treatment. With over 25 years of clinical practice, 2,500+ enlarged prostate procedures performed, and a career rooted in bringing advanced imaging technology directly into the urologist's office, Sethi straddles the worlds of clinical medicine and medical device innovation. Trained at UC Berkeley, St. Louis University, and Medical College of Wisconsin, he built Golden State Urology from a single Stockton practice in 2004 into a multi-location Northern California institution, and now serves as a clinical voice for a technology that is reshaping how prostate cancer is caught and treated.