Nilo Therapeutics is a New York-based biotechnology company developing a new class of medicines that target the brain-body neural circuits regulating the immune system. Building on discoveries that identified specific vagal neurons controlling systemic inflammation, Nilo aims to restore immune homeostasis centrally rather than broadly suppress the immune system, offering a differentiated approach to treating autoimmune and inflammatory disease. The company launched out of stealth in October 2025 with a $101 million Series A.
Kim Seth, Ph.D., is the founding President & CEO of Nilo Therapeutics, a New York biotech that launched in October 2025 with a $101 million Series A to build medicines that talk to the immune system through the brain. A Harvard-trained neurobiologist turned dealmaker, he spent 25-plus years moving between Goldman Sachs, Pfizer, and Repare Therapeutics - where he helped take a precision-oncology startup from pre-Series A to IPO - before betting his own career on the strange idea that the vagus nerve might be the most underused drug target in autoimmune disease.