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Excelsior Sciences

Excelsior Sciences is a New York City biotech building 'machine-native chemistry' - a way to make small molecules that machines can execute and AI can learn from. Its proprietary smart bloccs platform turns drug synthesis into a modular, automation-friendly, iterative process, closing the loop between AI-driven discovery and real-world manufacturing. Founded in 2024 and spun out of Deerfield Management, the company raised $95M in late 2025 to scale the platform and reshore U.S. drug discovery and production.

$25,000,000Grant (Empire State Development)

biotechnologysmall-moleculedrug-discoveryautomated-chemistrymachine-native-chemistrysmart-bloccs