Retro Biosciences is a clinical-stage longevity biotech in Redwood City, California with a single, unsubtle goal: add ten healthy years to the human lifespan. Founded in 2018 and launched publicly in 2021 with $180 million from OpenAI CEO Sam Altman, the company attacks aging at the cellular level across three platforms - autophagy enhancement, cellular reprogramming, and plasma-inspired therapeutics. Its lead drug, RTR242, an autophagy-restoring small molecule aimed at Alzheimer's disease, entered a first-in-human Phase 1 trial in 2025. A 2026 raise valued Retro at $1.8 billion.
Swamy Vijayan is the CEO and cofounder of Zafrens, a San Diego biotech reinventing drug discovery by shrinking a 96-well plate down to 200,000 microwells that image and sequence single cells at once. A physicist by training who admits he was driven less by a love of biology than by dissatisfaction with theoretical physics, he is a serial founder whose previous company Omniome sold to Pacific Biosciences for up to $800 million. His stated goal is not a quick exit but a foundation for smart people to do important things for the next 100 years.