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Tagged: neuropsychiatry
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Founder · Scientist · Executive
Sam Clark
Sam Clark, MD, PhD, is the founder and CEO of Terran Biosciences, a CNS-focused platform biotech he started in 2017 from his medical school dorm room with $10,000. A neuroscientist trained at MIT and Columbia, Clark has built one of the largest psychedelic development programs in the industry, is the named inventor on more than 200 patent applications, and holds the world's first patents for new forms of psilocybin and MDMA. Terran pairs a medicinal-chemistry drug design engine with an FDA-cleared neuroimaging software platform and a pipeline of late-stage assets licensed from Sanofi and Pierre Fabre.
sam clark · terran biosciencesRead →
Health · Enterprise
Autobahn Therapeutics, Inc.
Autobahn Therapeutics is a San Diego clinical-stage biotech building small-molecule medicines that reach the brain on purpose. Using a brain-targeting chemistry and prodrug platform, the company tunes where a drug goes - central versus peripheral - to unlock validated CNS biology that has been hard to drug safely. Its lead program, elunetirom (ABX-002), is an oral, once-daily, brain-penetrant CNS thyroid hormone receptor agonist in Phase 2 trials for major depressive disorder and bipolar depression, backed by more than $200 million in venture funding and a 2026 FDA Fast Track designation.
biotech · cnsRead →
Health
Newleos Therapeutics
Newleos Therapeutics is a Boston-based, clinical-stage biotechnology company building a new generation of treatments for neuropsychiatric disorders. Launched in February 2025 with an oversubscribed $93.5 million Series A, the company in-licensed four clinical-ready oral small molecules from Roche - targeting GABAA-y1, V1a, TAAR1, and GABAA-a5 - aimed at generalized anxiety, social anxiety, substance use disorders, and cognitive impairment. Its name nods to 'eos,' the Greek word for dawn: a new dawn for mental health treatment.
biotech · neuropsychiatryRead →
Founder · Executive · Scientist
Tom Large
Tom Large is the CEO and co-founder of Blue Oak Pharmaceuticals, a Waltham, Massachusetts startup hunting for the next generation of medicines for brain disorders. A neurobiologist by training, he spent two decades inside big pharma - leading neuroscience research at Eli Lilly and running preclinical research and translational medicine at Sunovion - before launching Blue Oak in 2016 to chase drugs with genuinely new mechanisms for bipolar depression, schizophrenia and treatment-resistant depression. His teams pioneered a target-agnostic approach to CNS drug discovery, and he later partnered with AI specialist Exscientia to design 'bispecific' small molecules that hit two targets at once.
tom large · thomas largeRead →
Health · Ai
Blue Oak Pharmaceuticals
Blue Oak Pharmaceuticals is a Waltham, Massachusetts biotech founded in 2016 to discover the next generation of drugs for brain disorders. Led by neurobiologist and former Eli Lilly and Sunovion executive Tom Large, the company designs novel, CNS-focused 'privileged chemotypes' and pairs them with systems-neurobiology behavioral assays and AI to hunt first-in-class small molecules for schizophrenia, bipolar disorder and treatment-resistant depression. Its work runs through partnerships with phenotypic-screening firm PsychoGenics and AI drug-design company Exscientia.
pharmaceuticals · drug discoveryRead →
Health · Ai · Hardware
Terran Biosciences
Terran Biosciences is a platform biotech developing therapeutics and technologies for neurological and psychiatric disease. It runs one of the industry's largest psychedelic development programs - psilocybin, LSD, MDMA derivatives and novel prodrugs - alongside late-stage schizophrenia assets licensed from Sanofi and Pierre Fabre, GMP psychedelic manufacturing, and NM-101, an FDA-cleared cloud platform for neuromelanin MRI analysis.
biotech · neuroscienceRead →
Health · Ai · Enterprise
Leal Therapeutics
Leal Therapeutics is a Worcester, Massachusetts biotech founded in 2021 by repeat CNS entrepreneur Asa Abeliovich, the scientist behind Prevail Therapeutics (acquired by Eli Lilly). Leal builds first-in-class neuro-metabolic medicines on a single idea: many brain diseases share a broken metabolism, and correcting those imbalances can treat conditions from schizophrenia to ALS. Backed by roughly $114M in total funding, its pipeline includes LTX-001, a brain-penetrant oral glutaminase inhibitor in the clinic, and LTX-002, an antisense oligonucleotide for ALS.
biotechnology · neuroscienceRead →
Executive · Operator · Founder
Timothy Noyes
Timothy Noyes is the President and CEO of Newleos Therapeutics, a Boston clinical-stage biotech that raised an oversubscribed $93.5M Series A to revive four neuropsychiatric compounds shelved by Roche. A Harvard-trained operator with three decades in biopharma, he has taken Proteon and Aerovate public, launched Renagel at GelTex/Genzyme, and built teams that carry molecules from bench to late-stage trials.
timothy noyes · newleos therapeuticsRead →