Holobeam Technologies is a Bethpage, New York biotech developing Holographic Energy Teleportation (HET), a patented method of focusing energy to precise microscopic locations inside the body. Paired with antibody-guided AdvaNan nanoparticles, the approach - branded the Holothermia protocol - aims to both detect individual cancer cells earlier than conventional imaging and heat them to death while sparing surrounding tissue. Founded by prolific inventor Gene Dolgoff, the LCD-projector pioneer who says he conceived the Star Trek Holodeck, the company is building HET-based MRI and portable scanners for diagnosis and treatment.
NVIGEN Inc. is a Sunnyvale, California nanobiotechnology company that engineers multifunctional, biodegradable magnetic and fluorescent nanoparticles for biomedical research, diagnostics and therapeutics. Built on its proprietary nanoparticle-imaging-delivery (NID) and MagVigen platforms, NVIGEN makes reagents and assays that capture DNA, RNA, proteins and rare cells from a single blood or tissue sample - powering liquid biopsy, NGS/multiomics sample preparation, single-cell spatial sequencing, and targeted drug and cell therapy. Its products are used by researchers at more than 40 institutions worldwide.
BreezeBio (formerly GenEdit) is a Brisbane, California-based biotechnology company that develops precision genetic medicines using its proprietary NanoGalaxy platform - a library of polymer nanoparticles capable of delivering genetic payloads like mRNA, siRNA, and CRISPR components to specific tissues without triggering immune responses. Unlike viral vectors that can only be dosed once and often provoke dangerous immune reactions, BreezeBio's non-viral approach allows repeat dosing, broad payload flexibility, and tissue selectivity across immune cells, heart, lung, and CNS. Founded in 2016 out of UC Berkeley by CEO Dr. Kunwoo Lee and CTO Dr. Hyo Min Park, the company rebranded from GenEdit in early 2026 following its $60M Series B, signaling a shift from delivery-platform licensor to full therapeutic developer with a lead program (BRZ-101) targeting Type 1 Diabetes.