movement-disorders
(3)
Neurocrine Biosciences
One movement-disorder medicine turned a San Diego research shop into a multibillion-dollar biopharma. Now Neurocrine is spending that advantage on rare endocrine disease, psychiatry and the difficult biology between brain and body.
Bernard Ravina
Bernard Ravina is a Johns Hopkins-trained neurologist who spent two decades treating people with dystonia before deciding the field needed a drug that did not yet exist. In 2025 he founded Vima Therapeutics in Cambridge, Massachusetts, and is its CEO, advancing VIM0423, a once-daily oral therapy aimed at the dopamine-acetylcholine imbalance behind movement disorders. The company emerged from stealth with a $60 million Series A, later extended to $100 million, and dosed its first Phase 2 dystonia patient in March 2026.
Vima Therapeutics
Vima Therapeutics is a Cambridge, Massachusetts clinical-stage biotechnology company developing VIM0423, a potential first-in-class once-daily oral therapy for isolated dystonia and Parkinson's disease. The drug selectively targets muscarinic cholinergic receptors in the brain to correct the dopamine-acetylcholine imbalance underlying these movement disorders. Incubated at Atlas Venture and led by neurologist Bernard Ravina, the company emerged from stealth in 2025 and has raised a $100 million Series A.