mechanical-thrombectomy
(2)
Penumbra, Inc.
Penumbra, Inc. is an Alameda, California medical device company that builds tools to pull life-threatening blood clots out of the body. Founded in 2004 by attorney-turned-CEO Adam Elsesser and neuro-interventional surgeon Dr. Arani Bose, it pioneered aspiration-based mechanical thrombectomy for acute ischemic stroke and expanded into peripheral, venous, and pulmonary clot removal with its Indigo and Lightning Flash systems. The company also runs an Immersive Healthcare arm using virtual reality (the REAL System) for rehabilitation and wellness. Public on the NYSE since 2015 under ticker PEN, Penumbra posted $1.4 billion in 2025 revenue and agreed in January 2026 to be acquired by Boston Scientific in a roughly $14.5 billion deal.
XCath Robotics
XCath Robotics is a Houston-based medical robotics company building next-generation endovascular robotic systems and steerable smart guidewires to treat stroke, brain aneurysms and other neurovascular conditions. Its flagship Iris system is the only endovascular robot in development capable of intracranial navigation, and the company is racing toward a clinical telerobot that could let a specialist perform a brain-clot removal on a patient hundreds of miles away.