Aluna is a San Francisco digital health company that turns daily breathing into data. Its FDA-cleared, palm-sized spirometer pairs with a gamified app and a clinician dashboard so people with asthma, COPD and cystic fibrosis - and their doctors - can track lung function (FEV1) at home and catch trouble before it becomes an emergency. Founded by three UC Berkeley alumni and originally named Knox Medical Diagnostics, Aluna raised about $27M total, including a $15.3M Series B in 2023, and was acquired by Huma in May 2025.
NuvoAir Medical is a virtual-first cardiopulmonary care company that helps patients with chronic heart and lung conditions - COPD, asthma, and CHF - manage their health from home before they end up in a hospital. Founded in Stockholm in 2015-2016 by Lorenzo Consoli and now headquartered in Boston, NuvoAir pairs FDA-cleared connected devices like the Air Next home spirometer with a clinical care team and data-driven monitoring. Its model is built around value-based care, with studies showing meaningful reductions in medical spend and hospitalizations. The company also powers decentralized clinical trials for pharma partners.
resbiotic is a physician-founded microbiome health company building clinically tested probiotics, prebiotics, postbiotics, and bioactive botanicals around its Gut-X Axis platform - the idea that the gut talks to the rest of the body. Its flagship resB Lung Support is positioned as the first clinically tested probiotic targeting the gut-lung axis for respiratory health. Founded in 2020 by physician-scientist Dr. C. Vivek Lal out of microbiome research at the University of Alabama at Birmingham, the company sells direct-to-consumer and through retail including Walmart and GNC, and has raised roughly $20.6M to date.