Plume Clinic is a Denver-based telehealth company built for and largely by the transgender community, offering gender-affirming hormone therapy, everyday medical care, medical letters of support, and community programming entirely through a phone. Founded in 2019 by physicians Dr. Jerrica Kirkley and Dr. Matthew Wetschler, Plume has served over 50,000 trans and gender non-conforming people across nearly every U.S. state, positioning itself as the first and largest health-tech company designed specifically for trans lives.
Alloy Health is a direct-to-consumer women's telehealth company built to fix how medicine treats menopause. Founded by Anne Fulenwider and Monica Molenaar, Alloy connects women in perimenopause and menopause with menopause-trained doctors and a full menu of FDA-approved, science-backed treatments - hormone replacement therapy, vaginal estrogen, plus hair, skin, sexual-wellness, gut and weight solutions - delivered to the door via an asynchronous platform with a flat $50 annual membership. The company raised a $16M Series A in November 2024 and reached profitability while serving women historically dismissed by the healthcare system.