Plume Clinic

Plume Clinic is a Denver-based telehealth company built for and largely by the transgender community, offering gender-affirming hormone therapy, everyday medical care, medical letters of support, and community programming entirely through a phone. Founded in 2019 by physicians Dr. Jerrica Kirkley and Dr. Matthew Wetschler, Plume has served over 50,000 trans and gender non-conforming people across nearly every U.S. state, positioning itself as the first and largest health-tech company designed specifically for trans lives.