It sells subscriptions to the past. With 30 billion records, the largest consumer DNA database around, and a growing stack of AI, Ancestry has quietly become one of the most durable businesses in consumer tech.
Imagene Labs is a Singapore-based health-tech company that runs an enterprise-grade, cloud-based B2B genetic analytics platform. Using patented ancestry-based genetic risk analytics and ethnically-relevant reference datasets, it turns a simple saliva sample into DNA insights that fitness, beauty, nutrition and healthcare brands use to build personalized products and services. Its consumer-facing brand, Ori, packages these insights into fitness, skincare and nutrition DNA tests for the Asian market and beyond.
Nucleus Genomics is a New York-based consumer genomics company that sells a $399 at-home, clinical-grade whole-genome sequencing kit and a software platform that turns a person's full DNA sequence into readable reports on disease risk, carrier status, traits, and longevity. Founded in 2021 by Thiel Fellow Kian Sadeghi, Nucleus pairs whole-genome data with polygenic risk scores and lifestyle inputs to estimate risk for common, complex conditions. In 2025 it expanded into reproductive products - carrier screening, partner DNA alignment, and a controversial embryo-ranking tool, Nucleus Embryo - that put the company at the center of a public debate over the science and ethics of genetic selection.
Kian Sadeghi is the founder and CEO of Nucleus Genomics, a New York biotech building consumer whole-genome sequencing that aims to put your DNA in your pocket. He dropped out of the University of Pennsylvania at 20, taught himself genetics across 18 notebooks in a Brooklyn year he hid from his parents, won a Thiel Fellowship, and raised roughly $32 million from Peter Thiel, Alexis Ohanian's Seven Seven Six, Balaji Srinivasan and Founders Fund. His mission traces to a cousin who died young of a suspected heart-rhythm disorder, and his blunt embrace of 'genetic optimization' has made him one of the most debated young founders in biotech.