dex
(5)
Sequence Markets
Sequence Markets is a New York and Toronto based trading-infrastructure startup (Y Combinator W26) that lets traders execute a single view across fragmented crypto venues - centralized exchanges, decentralized exchanges, perps, prediction markets, and tokenized assets - from one system. Its venue-neutral smart order router sits on proprietary low-latency infrastructure (roughly 2 microseconds internal latency, network paths up to 2.5x faster than the public internet) to find better prices and cut slippage, with access via terminal, API, SDK, and MCP for human traders, algorithmic systems, and AI agents.
dYdX
dYdX is a decentralized trading protocol best known for perpetual futures, where traders take leveraged long and short positions on crypto without handing custody to a centralized exchange. Founded by ex-Coinbase engineer Antonio Juliano in 2017, it evolved from an Ethereum DeFi app into its own sovereign Cosmos appchain (dYdX v4) that runs a high-performance, validator-operated order book settled in USDC. The protocol is governed by the DYDX token and, with the 2025 launch of spot trading, opened access to U.S. traders for the first time.
Ostium
Ostium is an onchain perpetuals exchange built on Arbitrum that lets anyone long or short real-world assets - stocks, commodities, indices, forex and crypto - directly from a self-custodial wallet, with up to 200x leverage and no broker in the middle. Founded by Harvard classmates and former Bridgewater hands Kaledora Kiernan-Linn and Marco Antonio Ribeiro, Ostium uses synthetic perpetuals and a custom oracle system to bring traditional markets onchain. It has processed tens of billions in cumulative trading volume and raised $27.8M total, including a $20M Series A co-led by General Catalyst and Jump Crypto in December 2025.
0x
0x is the open exchange infrastructure powering token swaps for many of crypto's largest apps - Coinbase, Robinhood, Phantom, MetaMask, Matcha and more. Through its Swap API, gasless transactions, and the underlying 0x Protocol, the company aggregates liquidity from hundreds of sources across the major chains so developers can ship trading experiences without building order routing themselves.
ControlUp
ControlUp is a digital employee experience (DEX) and autonomous endpoint management platform that helps IT teams see, score, and fix problems on every desktop, virtual session, and SaaS app before users start filing tickets. Born in Israel in 2008 and headquartered in San Francisco, it serves more than 2,000 enterprise customers and was named a Leader in the inaugural 2024 Gartner Magic Quadrant for DEX Tools.