Casana is a Rochester, New York digital-health company that builds the Smart Seat (originally the Heart Seat), a toilet-seat replacement that passively measures vital signs - heart rate, heart rate variability, blood oxygen, respiration rate and blood pressure insights - while a person simply sits, with no wearables, charging or behavior change required. Spun out of research done by founder Nicholas Conn during his PhD at the Rochester Institute of Technology, the company earned FDA 510(k) clearance in 2023 and launched a consumer version of the seat in July 2026.
Alio is a Broomfield, Colorado medical technology company that builds a non-invasive, continuous remote patient monitoring platform for people with chronic conditions. Its flagship SmartPatch - the world's first non-invasive potassium monitor - is worn over a patient's vascular access site and tracks metrics such as potassium, hemoglobin, hematocrit, heart rate, skin temperature and auscultation sounds, sending clinician-ready data to care teams via a bedside hub, cloud and portal. Founded in 2012 (originally as Graftworx) by David Kuraguntla and Samit Gupta, Alio focuses first on end-stage kidney disease and dialysis patients, aiming to replace infrequent blood draws with continuous data and cut avoidable hospitalizations.