cell-based-assays
(3)
Resonant Sensors Incorporated
Resonant Sensors Incorporated (RSI) is an Arlington, Texas biotechnology company that builds label-free optical biosensor systems based on its patented guided-mode resonance (GMR) technology. Its ResoSens Ultra-Mab Pro benchtop plate reader and disposable Bionetic microarray plates let researchers watch molecular binding interactions in real time, in a standard 96-well format, using tiny sample volumes and no fluorescent labels. RSI targets antibody discovery, epitope binning, hybridoma screening, kinetics and cell-based assays for immunotherapy, diagnostics and life-science research, and also offers analytical contract testing services.
Helena Mancebo
Helena Mancebo is the founder and CEO of Multispan, Inc., a Hayward, California biotech she has run for more than 20 years. She built a company around G protein-coupled receptors (GPCRs) - still among the most prolific class of drug targets - and grew it into a maker of the industry's largest collection of highly characterized human GPCR cell lines and 1,600-plus assay tools. A Yale-trained immunologist and geneticist, she pairs hard cell biology with a service obsession: next-day assay turnaround, native receptor pharmacology, and a culture built on empathy, integrity, and productivity. In 2023 Multispan's cell engineering and assay services were folded into Avantor's catalog; in 2025 she partnered with AI-automation firm Synfini to push GPCR drug discovery forward.
Zafrens
Zafrens is a San Diego biotechnology company building an ultra-high-throughput single-cell platform that isolates, images, runs assays on, and sequences millions of individual cells per day. Its Z-Screen technology swaps the conventional 96-well plate for a credit-card-sized plastic chip holding 50,000 to 200,000 microwells, each with integrated imaging and multi-omic sequencing. By linking perturbation to genotype, phenotype and function at single-cell resolution, Zafrens compresses multiple stages of drug discovery into a single benchtop experiment - a 500x to 2,000x jump in the number of experiments a scientist can run at one timepoint.