cancer-recurrence
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The Urine Test That Reads Cancer's Mail Twelve Years Early
No scope, no needle - just a cup of urine and 60 genes worth of warning. Convergent Genomics is betting that bladder cancer leaves a paper trail years before a doctor can see it.
SURGE Therapeutics
SURGE Therapeutics is a Cambridge, Massachusetts clinical-stage biotech building intraoperative immunotherapy: a biodegradable, injectable hydrogel (SURGERx) placed directly into the surgical wound at the moment a tumor is removed. The goal is to turn the body's post-surgical inflammation from immunosuppressive to immunostimulatory and stop residual cancer cells from seeding recurrence and metastasis. Founded on research from Harvard Medical School and led by founder-CEO Michael Goldberg, Ph.D., the company has raised about $58M and is advancing its lead candidate SRG-514 toward a registrational trial in triple-negative breast cancer.
Michael Goldberg
Michael Goldberg is the founder and CEO of SURGE Therapeutics, a Cambridge, Massachusetts biotech pioneering intraoperative immunotherapy. His idea is deceptively simple: when a surgeon removes a solid tumor, don't leave the cavity empty - fill it with an injectable, biodegradable hydrogel that releases immune-activating medicine right where cancer is most likely to return. A trained chemist who earned a PhD at MIT under Robert Langer and did postdoctoral work with Nobel laureate Phillip Sharp, Goldberg became a Harvard Medical School professor before leaving academia to translate his lab's discovery into the clinic. SURGE has raised roughly $58M, cleared an FDA IND, and completed Phase 1 dosing of its lead program ahead of a registrational trial in triple-negative breast cancer.