
A chemist who spent years trying to make fuel from plants found a more useful reversal: make protein from methane. Alan Shaw’s second biotech act is a lesson in recognizing the market hiding inside the science.
Calysta is a San Mateo, California biotechnology company that uses a patented gas-fermentation platform to turn methane into FeedKind, a single-cell protein for aquaculture, livestock and pet feed - and increasingly human food. Its bacteria eat natural gas instead of arable land, plants or animals, producing protein with a low environmental footprint. Backed by Cargill, BP and Temasek and partnered with Adisseo through the Calysseo joint venture, Calysta opened the world's first industrial-scale single-cell protein plant in Chongqing, China in 2022.