For decades, David Albert carried the same stubborn idea: serious medical signals should travel. One homemade video, one accidental LinkedIn share and an iPhone 4 finally gave the idea somewhere to go.

From satellite television to a pocket-sized ECG company, Locke's career has followed one durable idea: complicated products still need plain language, disciplined launches and a reason for people to care.

Before she ran AliveCor, Priya Abani wrote validation tools for microprocessors and helped Alexa escape the Echo. Her career is a study in one portable skill: making complicated technology useful to ordinary people.