NeuShen Therapeutics is a clinical-stage biotech developing novel small-molecule and gene-therapy treatments for central nervous system disorders such as schizophrenia, depression and epilepsy. Founded in 2021 by Joan Huaqiong Shen, MD, PhD, and headquartered in Shanghai with an R&D center in the Boston area, the company runs a pipeline led by NS-136, a selective M4 receptor positive allosteric modulator for schizophrenia, and NS-041, a highly selective KCNQ2/3 activator for epilepsy and depression.
Avenue Biosciences is a transatlantic biotech building the first platform to measure and modulate the cellular secretory pathway at scale. Spun out of the University of Helsinki and headquartered between Helsinki and Palo Alto, the company pairs high-throughput chemistry with machine learning to design signal peptides and boost yields of therapeutic proteins - biologics, biosimilars, and mRNA-encoded medicines - so that production bottlenecks stop limiting which therapies reach patients.