Breaking
$52M SERIES A - Medra closes December 2025 round led by Human Capital Total funding now ~$63M Robots at Genentech & Addition Therapeutics benches Medra Lab 001 - 38,000 sq ft going up in San Francisco Robots operate 75%+ of standard lab instruments Directed in plain English, no code required $52M SERIES A - Medra closes December 2025 round led by Human Capital Total funding now ~$63M Robots at Genentech & Addition Therapeutics benches Medra Lab 001 - 38,000 sq ft going up in San Francisco Robots operate 75%+ of standard lab instruments Directed in plain English, no code required
The Physical AI Dispatch San Francisco Company Profile Vol. I

Hand Over
the Lab Work

Medra builds robots that do biology - vision-guided machines that pipette, culture cells and edit genes, all directed in plain English. It is trying to turn the wet lab into something that runs itself.

Medra logo
Exhibit AThe wordmark of a company that would rather you never touch a pipette again. Medra, founded 2021, keeps its robots busy while its logo sits still.

$63M
Total Raised
~58
Employees
5
Units Deployed
2021
Founded

The Story

A robotics PhD decided the problem with AI in biology was that it never picks up a pipette.

There is a durable joke in drug discovery, which is that the industry spends 10 to 15 years and something north of $2 billion to bring a single drug to market, and much of that time is spent doing the same manual bench work over and over while an enormous amount of the data - the failed runs, the botched pipetting, the timing that was slightly off - gets thrown directly in the trash. This is, if you think about it, a strange way to run an information business.

Medra's argument is that biology is, secretly, a robotics problem. Not a modeling problem, not a compute problem - a robotics problem. You can build an AI that proposes a thousand experiments, but if a human has to run all thousand by hand, you have not actually sped anything up. You have just made a very well-read intern who cannot use their hands.

So Medra built the hands. The company calls the result a Physical AI Scientist: a system that unifies robotics, reasoning and data generation into one continuous loop. It designs an experiment, a robot executes it, cameras and sensors watch what happened, the result feeds back into the model, and it tries again - overnight, on weekends, without asking for a coffee break.

The founder is Michelle Lee, who did her PhD at the Stanford AI Lab on physical AI and reinforcement learning, and who had, by 2022, done the hard part of an academic career: she had an assistant professorship at NYU lined up. She left it. The bet was that the interesting version of robotics was not going to happen inside a university lab, and that the place it would happen was the wet bench, where the data is hardest to fake and hardest to get.

What makes this more than a pitch deck is that the robots do not use custom hardware for every task. They have learned to operate more than 75% of standard laboratory instruments - the same machines a human scientist already owns - and they are told what to do in plain English, roughly the way you would text instructions to a lab mate. The technical name Medra uses is a vision-language-lab-action model, which is a mouthful, but the idea is simple: the machine watches, it listens, and it moves.

The commercial discipline is worth noting too. Medra does not do free pilots. Its early customers are paying biopharma partners - among them Genentech, the Roche subsidiary, and Addition Therapeutics - which is a useful filter, because the people who invented modern biotech are not easily impressed by a demo. As of late 2025 there were five units running at partner sites across the US, and the company had raised about $63 million to build one of the largest autonomous labs in the country.

"AI will not transform drug discovery if it never leaves the screen - it has to be directly integrated into the physical execution of experiments in the lab." - Michelle Lee, Founder & CEO

The Product

Three systems, one loop.

Medra splits the work into a reasoning brain and a set of hands, then wires them together so results from the bench flow back into the next experiment.

Layer 01

Physical AI

Vision-guided robotic workcells that execute protocols, operate standard instruments, and catch their own mistakes with computer vision. They log the granular stuff - pipette angle, well depth, reagent timing, mixing speed.

Layer 02

Scientific AI

The reasoning layer. Program protocols in natural language, reason across data, images and protocols at once, and run closed-loop optimization so the system improves the experiment as it goes.

Layer 03

AI Experimentalist

The part that acts like an actual scientist: it designs, executes, interprets and improves experiments continuously - no human handoff between forming a hypothesis and testing it.

What you can actually run on it

Nucleic acid extraction RNA transfection NGS library prep iPSC differentiation Tissue staining Gene expression analysis Cell viability testing Cell culture CRISPR-Cas9 editing Protein purification

The Insight

The bottleneck isn't compute. It's the data pharma throws away.

Everyone building AI for science hits the same wall: the models are hungry for real experimental data, and biology's most valuable data - the failures, the near-misses, the runs that didn't work - is exactly what labs discard and never publish.

Medra's robots log all of it. Every step, every failed run, every off-by-a-little measurement becomes training fuel. In a field obsessed with bigger models, Medra's quieter bet is that the scarce resource is the exhaust of the experiment itself.

By the numbers

Why the loop matters

10-15 yrs  typical drug development timeline

$2B+  average cost to bring one drug to market

24/7  robots run overnight and weekends, alerting on problems

75%+  of standard lab instruments the robots can operate


The Money

From an $11M seed to a $52M Series A in one quarter.

Seed • Sep '25
$11M
Series A • Dec '25
$52M

The December 2025 Series A was led by Human Capital, with existing backers returning and a roster of new names joining. Total capital raised sits at roughly $63 million, earmarked for expanding partnerships and building Medra Lab 001.

Human Capital Lux Capital Neo NFDG Catalio Capital Menlo Ventures 776 Fusion Fund

The Customers

Paying partners only. No free pilots.

GenentechThe Roche subsidiary runs Medra robotic units at its sites - an early, demanding biopharma partner.
Addition TherapeuticsBiotech partner deploying Medra systems into its research workflows.
CultivariumMicrobial research organization using Medra automation for discovery work.

The Founder

Michelle Lee

Founder and CEO. Stanford PhD out of the AI Lab, where she worked on physical AI, robotics and reinforcement learning. Before Medra she passed through NVIDIA, SpaceX and McKinsey, and had accepted an assistant professorship at NYU in computer science and electrical & computer engineering.

She left academia in 2022 to start Medra, and now runs it from San Francisco's Mission District. She has told the story of that decision - "from conviction to company" - on Stanford's Technology Ventures Program stage and speaks at the BIO International Convention.

"To accelerate drug development, we need to link predictions directly to automated execution." - Michelle Lee

The Timeline

How it got here.

2021

Medra is founded in San Francisco.

2022

Michelle Lee leaves a planned NYU professorship to build the company full time.

Late 2024

First robotic workcells deployed to biopharma customers.

Sep 2025

Closes an $11M seed round with Lux Capital, Neo and NFDG.

Dec 2025

Announces $52M Series A led by Human Capital; total funding reaches ~$63M. Five units running across US partner sites.

Feb 2026

Leases a San Francisco industrial building for Medra Lab 001 - a 38,000 sq ft autonomous lab for hundreds of robots.


The Margins

Things worth knowing.

Link copied to clipboard