Company Profile - Digital Health
Oshi Health
The virtual GI clinic for the one in four Americans whose digestive system has its own opinions.
The virtual GI clinic for the one in four Americans whose digestive system has its own opinions.
Somewhere right now, a person is sitting on a bathroom floor at 2 a.m., googling symptoms that no search bar can fix. The traditional answer is a referral, a three-month wait, a fifteen-minute appointment, and a follow-up scheduled for never. Oshi Health decided that was an unacceptable answer.
Today Oshi is an in-network virtual gastrointestinal clinic available in all 50 states and Washington D.C., reachable by anyone whose health plan or employer has signed on - roughly 40 million people and counting. Open the app and you are not handed a chatbot. You are introduced to an actual team: a board-certified gastroenterologist, an advanced-practice provider, a registered dietitian, a behavioral-health specialist trained in the gut-brain connection, and a care coordinator who remembers your name. Visits are virtual. Messaging is unlimited. The wait is measured in days, not seasons.
"Bringing center-of-excellence quality GI care to people - wherever they are."
Digestive disease is the condition polite society agreed not to discuss. That silence is expensive. Two out of three Americans report digestive symptoms in any given week. One in four lives with a diagnosed GI condition - Crohn's, ulcerative colitis, IBS, GERD, SIBO, or the vast grey country of "we ran tests and found nothing." The national bill runs past $136 billion a year.
The strange part is that the money is mostly wasted. Patients bounce between specialists, collect redundant scopes and scans, land in the ER when a flare hits at midnight, and rarely get the one thing that works: coordinated care that treats diet, behavior, and biology as a single problem. Gastroenterologists are scarce, booked, and paid to perform procedures - not to talk you through a low-FODMAP week or the anxiety that tightens your stomach. The system was built to find polyps, not to make people feel better.
"Two out of three Americans have weekly digestive symptoms. The care system has, charmingly, decided this is fine."
Oshi began in 2020 with two people who saw the same problem from opposite ends. Sam Holliday had spent a decade scaling AOL, then crossed into value-based healthcare at Aledade, Avalere, and Audacious Inquiry before running the Florida market for one of the country's largest independent primary-care groups. He understood the unglamorous machinery of getting paid to keep people well. Dr. Sameer Berry is a gastroenterologist and physician-scientist with more than 25 peer-reviewed papers, who runs randomized controlled trials on digital health and alternative payment models. He understood the medicine, and the evidence required to prove it.
Their bet was contrarian in a sector addicted to shortcuts: build the clinical team in-house rather than renting a network of contractors, and refuse to launch a claim Oshi could not back with a study. Most digital-health startups grow first and gather evidence later, if ever. Oshi inverted it. The thesis was that rigorous, multidisciplinary, whole-person GI care would not only help patients but cost payers less - and that you could measure both.
Ex-AOL operator turned value-based-care builder. Spent years on the business of keeping people healthy before deciding the gut deserved its own clinic.
Gastroenterologist, physician-scientist, 25+ peer-reviewed papers. Named to Modern Healthcare's 50 Most Influential Clinical Executives.
"Building our own multidisciplinary clinical team is the bedrock of our outcomes."
Oshi's product is deceptively simple to describe and hard to copy: a virtual clinic where a single coordinated team treats the whole person. The gut-brain connection is not a marketing line here - the behavioral-health specialist is a core team member, because stress and digestion are not separate appointments. Diet is handled by a registered dietitian, not a pamphlet. And a gastroenterologist oversees it all, so the plan holds together.
Diagnosis and treatment for IBS, IBD, GERD, SIBO, and undiagnosed symptoms - with unlimited virtual visits and messaging.
GI doctors, advanced-practice providers, dietitians, gut-brain specialists, and care coordinators - employed, not outsourced.
Diet, behavior, medication, and biology treated together, integrated with your existing plan, employer, or local GI practice.
Most health-tech pitches lean on a hopeful slide. Oshi leaned on a clinical trial. In an analysis by a national health plan of a large commercially insured population, 92% of Oshi members reported symptom improvement and 98% reported satisfaction. The financial result was the one that made investors lean in: total medical-cost savings of $10,292 per patient over six months, driven by fewer avoidable scopes, scans, ER visits, and prescriptions. According to reporting, the Series C was not even planned - investors came knocking after seeing the data.
"A $60M round nobody set out to raise. The clinical evidence, it turns out, makes a persuasive cold email."
The believers are telling. The cap table includes Oak HC/FT, CVS Health Ventures, Takeda Digital Ventures, Bessemer, Flare Capital, and Frist Cressey - and, unusually, the two largest U.S. gastroenterology societies, the American College of Gastroenterology and the American Gastroenterological Association. When the establishment of a medical specialty invests in a startup challenging how that specialty is delivered, it is worth noticing. Employer partners now include Dayforce, Koch Inc., Mariner, Nielsen, and TE Connectivity.
Oshi's stated aim is to increase access to high-quality, coordinated digestive care while lowering its total cost - and to prove both with evidence rather than assertion. The deeper ambition is structural. Oshi wants whole-person GI care to be normal: in-network, reimbursed, and held to the same outcomes bar as any center of excellence. The 2025 plan to expand into Medicare populations is the next test of whether the model travels beyond the commercially insured.
Return to that person, awake and afraid, scrolling for an answer. In the old story, they wait three months, get fifteen minutes, and learn nothing they can use that night. In Oshi's version, they message a care team that already knows their history, get a dietitian's plan and a clinician's reassurance within days, and stay out of the ER entirely. The flare still happens. What changes is whether anyone competent is there for it.
That is the whole argument, and Oshi has put numbers under it: 92% better, 98% satisfied, $10,000 saved, 50 states reached. Digestive disease will not be cured by an app, and Oshi does not pretend otherwise. But the quiet, expensive, embarrassing problem of American gut health finally has a clinic built around the patient instead of the procedure - and a balance sheet that says doing it right is also cheaper. The 2 a.m. floor is still cold. For a growing number of people, it is no longer lonely.
"The gut got a real doctor's office. It just happens to live in your pocket."