He drafts post-human heist novels before breakfast and runs an mRNA biotech the rest of the day. Both jobs are about rewriting reality from code.
Hannu Rajaniemi // the man with two notebooks
Most CEOs do not keep a string-theory dissertation and a heist novel on the same shelf. Hannu Rajaniemi does, and he treats the two as the same skill. He runs HelixNano, a synthetic-biology startup chasing what he calls a unified interface to the immune system - mRNA you can program the way you'd write code. The pitch is plain: identify the mutations in a patient's tumor, then use mRNA to make the cell display a "mugshot" the immune system learns to hunt.
That is the day job. The other one made his name. In 2010 he published The Quantum Thief, a debut set in a post-human solar system where memory is currency and a master criminal named Jean le Flambeur breaks out of a prison built from game theory. Readers either bounced off the unexplained jargon or fell hard for it. Enough fell hard that the book now exists in more than twenty languages, and the trilogy that followed - The Fractal Prince and The Causal Angel - turned a Finnish mathematician into a fixture of literary science fiction.
"These systems are made out of stories. They are made out of stories."
He says that line about biology, but it could be a thesis for his whole career. Rajaniemi grew up in Ylivieska, a small town in northern Finland, and credits Jules Verne for sending him in two directions at once - into science, and into writing about it. He stacked degrees the way other people collect stamps: a BSc in mathematics from Oulu, a Certificate of Advanced Study from Cambridge, and a PhD in mathematical physics from Edinburgh, where the subject was string theory. Somewhere in there he did national service as a research scientist for the Finnish Defence Forces.
Edinburgh did something the equations didn't. "I realized I wanted to start writing when I moved to Edinburgh to do my PhD," he has said. He found a local writers' group, Writers' Bloc, after wandering into a reading by Charles Stross, and started producing the short fiction that became his calling card. His first published story, "Shibuya No Love," appeared in 2003.
The break reads like a tall tale and isn't. In 2008 his agent shopped roughly twenty-four double-spaced pages of an unfinished manuscript, and the British publisher Gollancz signed him to a three-book deal on the strength of those pages alone. He had to go write the rest.
"In Finnish, it's easy to make up new words and string them together to make compound words, which makes it a nice language for science fiction."
And yet he writes the novels in English, his second language. He describes the split with a clarity most bilingual people only feel: "My Finnish-speaking self is the friends and family self, whereas in all professional settings I'm one hundred percent English speaking." The distance, he argues, is useful. One language for warmth, another for work and worlds.
Before the lab coat there was a whiteboard. He was a founding director of ThinkTank Maths, a commercial research outfit that sold hard mathematics to industry. Then in 2013 he co-founded HelixNano and pointed the same toolkit at biology, betting that an immune system is just another system you can learn to address.
The bet got tested in public. When COVID-19 arrived in early 2020, his team recognized their platform applied to a coronavirus vaccine and committed within a week. They had animal immune-response data on their first candidates inside five weeks. The work continued past the headlines: by February 2024 HelixNano had moved an mRNA COVID-19 vaccine candidate into a Phase I trial in Australia, and the company has talked openly about vaccines that resist freezing and skip the needle - the kind you could ship anywhere without a cold chain.
He never stopped writing through any of it. Summerland, a 1938 spy novel set in a world where the afterlife is a mapped, bureaucratic place, arrived in 2018. Darkome followed in 2024, dragging his fiction closer to the biotech he actually builds. Morning pages, he insists, are not a distraction from the company. "It's nice to treat writing as this meditative space in the morning that allows me to get away from the stress of the day job."
The through-line is a refusal to pick a lane. Physicist, novelist, founder - he keeps insisting the categories are smaller than the person. He is, in the end, a builder of systems who happens to think the most powerful system anyone has invented is still the story.
HelixNano, founded 2013, is chasing a programmable mRNA platform - personalized cancer vaccines that hand the immune system a tumor's "mugshot," and infectious-disease vaccines designed to survive without a cold chain. In 2020 the team pivoted to COVID-19 in a week; by 2024 a candidate reached a Phase I trial in Australia.
Four novels and counting. The Quantum Thief (2010) launched a post-human trilogy translated into 20+ languages and crowned with Finland's Tahtivaeltaja Award. Summerland (2018) mapped a civil-service afterlife; Darkome (2024) pulled the fiction toward the biology he now lives inside.
These systems are made out of stories. They are made out of stories.
I realized I wanted to start writing when I moved to Edinburgh to do my PhD.
In Finnish, it's easy to make up new words and string them together to make compound words, which makes it a nice language for science fiction.
My Finnish-speaking self is the friends and family self, whereas in all professional settings I'm one hundred percent English speaking.
It's nice to treat writing as this meditative space in the morning that allows me to get away from the stress of the day job.
Having that one degree of distance from the text actually made it easier to edit and accept feedback.
Jules Verne sent him in two directions at once - into a science career and into writing science fiction.
He writes his novels in English, not his native Finnish, and finds the distance useful for editing.
He completed national service as a research scientist for the Finnish Defence Forces.
He was a founding director of ThinkTank Maths, a firm selling hard mathematics to industry.
His Edinburgh writers' group, Writers' Bloc, also counted author Charles Stross among its members.
HelixNano's vaccine idea: show the immune system a tumor's "mugshot" via programmable mRNA.
mRNA and the Future of Biotechnology with Hannu Rajaniemi - a conversation on programmable biology.
On being a sci-fi author and biotech entrepreneur - Existential Hope.
Spies, Radios, and the Afterlife - Clarkesworld Magazine.