# Yoneda Labs

> Yoneda Labs is building the foundation model for chemical manufacturing - think of it as the AI brain that tells chemists exactly which conditions to use to make a reaction work, before they spend months running dead-end experiments. Founded by three Cambridge graduates and backed by Khosla Ventures and Y Combinator, the company's software suite (Predict, Optimize, Analyze) compresses reaction optimization timelines from months to days. Their first named partnership with Symeres pushed cross-coupling reaction yields from ~30% to over 90%. The goal: become the universal AI layer for the $5 trillion chemical industry.

- **Founded:** 2023
- **Headquarters:** San Francisco, CA, USA
- **Founders:** Michal Mgeladze-Arciuch (Co-Founder & CEO), Jan Oboril (Co-Founder & Chief Scientist), Daniel Vlasits (Co-Founder & CTO)
- **Team size:** 3-5 (co-founders plus early hires; actively hiring organic chemists)
- **Products:** Yoneda Optimize, Yoneda Predict, Yoneda Analyze
- **Notable:** Accepted into Y Combinator Winter 2024 batch, Raised $4M seed round led by Khosla Ventures (April 2024), Symeres partnership: boosted cross-coupling reaction yields from ~30% to >90%

## Products & services

- **Yoneda Optimize** — Flagship desktop application (fully offline for data privacy). Uses statistical and ML algorithms to suggest which experiments to run next, incorporating chemical property descriptors. Cuts reaction optimization from months to days.
- **Yoneda Predict** — Forecasts reliable conditions for novel reactions before running any experiments. Trained on tens of thousands of experimentally-generated data points. Helps teams identify lead compounds faster and synthesize more analogs.
- **Yoneda Analyze** — Automates LCMS (liquid chromatography/mass spectrometry) spectra analysis. Detects overlapping peaks and integrates data. Saves approximately 5 minutes per chromatogram.

## Achievements

- Accepted into Y Combinator Winter 2024 batch
- Raised $4M seed round led by Khosla Ventures (April 2024)
- Symeres partnership: boosted cross-coupling reaction yields from ~30% to >90%
- Jan Oboril ranked 8th, 10th, and 11th at the International Chemistry Olympiad across three consecutive years
- Daniel Vlasits won Pi Wars robotics competition
- Built proprietary wet lab to generate training data for their foundation model
- Exhibited at BIO International Convention 2025

## Latest updates

- **2025-05** — Published Symeres case study showing cross-coupling reaction yields improved from ~30% to >90% using Yoneda Optimize
- **2025** — Exhibited at BIO International Convention 2025
- **2024-04** — Closed $4M seed round led by Khosla Ventures with participation from 500 Emerging Europe, 468 Capital, Fellows Fund, and Y Combinator
- **2024-01** — Joined Y Combinator Winter 2024 batch and launched publicly with 'Foundation Model for Chemical Reactions' announcement

## Links

- Website: https://www.yonedalabs.com/
- LinkedIn: https://www.linkedin.com/company/yonedalabs
- Twitter/X: https://x.com/yonedalabs

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Profile page: https://yespress.io/yoneda-labs
Published by YesPress — https://yespress.io
Last updated: 2026-04-27